子宫内膜异位症的非侵入性检查在这里；它们的可靠性有多高，我们应该如何处理结果？

IF 1.4 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Australian & New Zealand Journal of Obstetrics & Gynaecology Pub Date : 2023-11-07 DOI:10.1111/ajo.13765

Simon M. Scheck, Claire Henry, Nick Bedford, Jason Abbott, Michael Wynn-Williams, Anusch Yazdani, Simon McDowell

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引用次数: 0

摘要

子宫内膜异位症的可靠非侵入性生物标志物很可能在未来几年出现。在此之前，临床医生需要意识到商业上可获得的测试，意识到支持这些测试的证据水平，并准备好为提供此类测试结果的患者提供咨询和管理。一种在欧洲越来越受欢迎的测试是使用基于机器的学习算法开发的，该算法基于法国200名疑似子宫内膜异位症患者的队列分析了数千个微小RNA。我们探索了这种商业可用测试的背景科学；概述有待回答的问题；并注意不要在研究环境之外使用它。

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Non-invasive tests for endometriosis are here; how reliable are they, and what should we do with the results?

A reliable non-invasive biomarker for endometriosis is highly likely in the coming years. In the lead-up to this, clinicians need to be aware of commercially available tests as they become accessible, be aware of the level of evidence to support them and be prepared to counsel and manage patients who present with the results of such tests. One such test gaining popularity in Europe was developed using a machine-based learning algorithm to analyse thousands of microRNAs based on a 200-patient cohort with suspected endometriosis in France. We explore the background science for this commercially available test; outline the questions that remain to be answered; and caution against its use outside of a research setting.

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来源期刊

Australian & New Zealand Journal of Obstetrics & Gynaecology 医学-妇产科学

CiteScore

3.40

自引率

11.80%

发文量

165

审稿时长

4-8 weeks

期刊介绍： The Australian and New Zealand Journal of Obstetrics and Gynaecology (ANZJOG) is an editorially independent publication owned by the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) and the RANZCOG Research foundation. ANZJOG aims to provide a medium for the publication of original contributions to clinical practice and/or research in all fields of obstetrics and gynaecology and related disciplines. Articles are peer reviewed by clinicians or researchers expert in the field of the submitted work. From time to time the journal will also publish printed abstracts from the RANZCOG Annual Scientific Meeting and meetings of relevant special interest groups, where the accepted abstracts have undergone the journals peer review acceptance process.