针对心肌病铁下垂的治疗方法。

IF 3.1 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Drugs and Therapy Pub Date : 2025-06-01 Epub Date: 2023-11-06 DOI:10.1007/s10557-023-07514-4

Yanqian Ruan, Ling Zhang, Lina Zhang, Keyang Zhu

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引用次数: 0

摘要

心肌病是指一组随着时间的推移会导致严重心力衰竭的心脏病。心肌病已被证明与脱铁症有关，脱铁症是一种非细胞凋亡形式的细胞死亡。研究表明，一些小分子药物和草药活性成分可以调节脱铁性贫血，从而缓解心肌病的发展。本文综述了近年来关于脱铁性心肌病的发现，其在心肌病发病机制中的作用，以及治疗脱铁性相关心肌病的治疗选择。本文旨在深入了解脱铁性贫血的基本机制及其预防心肌病和相关疾病的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Therapeutic Approaches Targeting Ferroptosis in Cardiomyopathy.

查看原文本刊更多论文

Therapeutic Approaches Targeting Ferroptosis in Cardiomyopathy.

The term cardiomyopathy refers to a group of heart diseases that cause severe heart failure over time. Cardiomyopathies have been proven to be associated with ferroptosis, a non-apoptotic form of cell death. It has been shown that some small molecule drugs and active ingredients of herbal medicine can regulate ferroptosis, thereby alleviating the development of cardiomyopathy. This article reviews recent discoveries about ferroptosis, its role in the pathogenesis of cardiomyopathy, and the therapeutic options for treating ferroptosis-associated cardiomyopathy. The article aims to provide insights into the basic mechanisms of ferroptosis and its treatment to prevent cardiomyopathy and related diseases.

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来源期刊

Cardiovascular Drugs and Therapy 医学-心血管系统

CiteScore

8.30

自引率

0.00%

发文量

110

审稿时长

4.5 months

期刊介绍： Designed to objectively cover the process of bench to bedside development of cardiovascular drug, device and cell therapy, and to bring you the information you need most in a timely and useful format, Cardiovascular Drugs and Therapy takes a fresh and energetic look at advances in this dynamic field. Homing in on the most exciting work being done on new therapeutic agents, Cardiovascular Drugs and Therapy focusses on developments in atherosclerosis, hyperlipidemia, diabetes, ischemic syndromes and arrhythmias. The Journal is an authoritative source of current and relevant information that is indispensable for basic and clinical investigators aiming for novel, breakthrough research as well as for cardiologists seeking to best serve their patients. Providing you with a single, concise reference tool acknowledged to be among the finest in the world, Cardiovascular Drugs and Therapy is listed in Web of Science and PubMed/Medline among other abstracting and indexing services. The regular articles and frequent special topical issues equip you with an up-to-date source defined by the need for accurate information on an ever-evolving field. Cardiovascular Drugs and Therapy is a careful and accurate guide through the maze of new products and therapies which furnishes you with the details on cardiovascular pharmacology that you will refer to time and time again.