伴有进行性核上性麻痹和路易体病理学表现为局限性视觉记忆丧失：一例临床病理病例。

IF 5.8 2区医学 Q1 CLINICAL NEUROLOGY

Brain Pathology Pub Date : 2023-11-05 DOI:10.1111/bpa.13219

Christopher Kobylecki, Jennifer C. Thompson, Andrew C. Robinson, Federico Roncaroli, Julie S. Snowden, David M. Mann

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引用次数: 0

摘要

一名70岁的男性因视觉记忆受损而就诊，影像学上主要表现为右侧近中颞叶萎缩。他在症状出现6年后死亡，神经病理学检查显示伴有进行性核上性麻痹和路易体病理。尽管他在出现这两种情况时都不符合临床标准，但我们认为中颞区两种病理之间的相互作用可能导致这种非典型临床表型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Concomitant progressive supranuclear palsy and Lewy body pathology presenting with circumscribed visual memory loss: A clinicopathological case

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Concomitant progressive supranuclear palsy and Lewy body pathology presenting with circumscribed visual memory loss: A clinicopathological case

A 70-year-old man presented to the clinic with impairment of visual memory and marked predominantly right sided mesial temporal lobe atrophy on imaging. He died 6 years following symptom onset and neuropathological examination showed concomitant progressive supranuclear palsy and Lewy body pathology. Although he did not fulfil clinical criteria for either condition at presentation, we propose that interactions between the two pathologies in mesial temporal regions could result in this atypical clinical phenotype.

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来源期刊

Brain Pathology 医学-病理学

CiteScore

13.20

自引率

3.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Brain Pathology is the journal of choice for biomedical scientists investigating diseases of the nervous system. The official journal of the International Society of Neuropathology, Brain Pathology is a peer-reviewed quarterly publication that includes original research, review articles and symposia focuses on the pathogenesis of neurological disease.