{"title":"玉米丝多糖对2型糖尿病大鼠转化生长因子-β1信号通路的影响。","authors":"Xianchun Wen, Liling Yue","doi":"10.2174/1874120701509010204","DOIUrl":null,"url":null,"abstract":"<p><p>In prevention stage, comparing with normal control group, triglycerides, blood sugar (BG), 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group, but weight and urea nitrogen (BUN) was less in it. 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group than the intervention group. 24-hour urinary protein and BG in the intervention group were higher than normal control group, but BUN is less than normal control group; In the intervention group the weight of kidney and weight of rat were also higher than T2DM group, but CHO and 24-hour urinary protein were less than T2DM group. The expression of TGF-β1 in T2DM group were more than the other groups. In treatment stage, serum creatinine (Cr), weight, BG and CHO, TGand 24-hour urinary protein quantitative were significantly higher in the DN rats than those in the normal control rats (P>0.05). The expression level of TGF-β1 and triglyceride level in the corn silk dihydroxycorn silk3 treated group were obviously lower than those in the DN rats. </p>","PeriodicalId":39121,"journal":{"name":"Open Biomedical Engineering Journal","volume":"9 ","pages":"204-8"},"PeriodicalIF":0.0000,"publicationDate":"2015-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874120701509010204","citationCount":"7","resultStr":"{\"title\":\"The Influence of Corn Silk Polysaccharide on Signal Pathway of TGF-β1 in Type 2 Diabetic Mellitus Rat.\",\"authors\":\"Xianchun Wen, Liling Yue\",\"doi\":\"10.2174/1874120701509010204\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In prevention stage, comparing with normal control group, triglycerides, blood sugar (BG), 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group, but weight and urea nitrogen (BUN) was less in it. 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group than the intervention group. 24-hour urinary protein and BG in the intervention group were higher than normal control group, but BUN is less than normal control group; In the intervention group the weight of kidney and weight of rat were also higher than T2DM group, but CHO and 24-hour urinary protein were less than T2DM group. The expression of TGF-β1 in T2DM group were more than the other groups. In treatment stage, serum creatinine (Cr), weight, BG and CHO, TGand 24-hour urinary protein quantitative were significantly higher in the DN rats than those in the normal control rats (P>0.05). The expression level of TGF-β1 and triglyceride level in the corn silk dihydroxycorn silk3 treated group were obviously lower than those in the DN rats. </p>\",\"PeriodicalId\":39121,\"journal\":{\"name\":\"Open Biomedical Engineering Journal\",\"volume\":\"9 \",\"pages\":\"204-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2174/1874120701509010204\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Biomedical Engineering Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874120701509010204\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Biomedical Engineering Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874120701509010204","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
The Influence of Corn Silk Polysaccharide on Signal Pathway of TGF-β1 in Type 2 Diabetic Mellitus Rat.
In prevention stage, comparing with normal control group, triglycerides, blood sugar (BG), 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group, but weight and urea nitrogen (BUN) was less in it. 24-hour urinary protein and cholesterol (CHO) were higher in T2DM group than the intervention group. 24-hour urinary protein and BG in the intervention group were higher than normal control group, but BUN is less than normal control group; In the intervention group the weight of kidney and weight of rat were also higher than T2DM group, but CHO and 24-hour urinary protein were less than T2DM group. The expression of TGF-β1 in T2DM group were more than the other groups. In treatment stage, serum creatinine (Cr), weight, BG and CHO, TGand 24-hour urinary protein quantitative were significantly higher in the DN rats than those in the normal control rats (P>0.05). The expression level of TGF-β1 and triglyceride level in the corn silk dihydroxycorn silk3 treated group were obviously lower than those in the DN rats.
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