肌肉力量在帕金森病患者坐立任务中的作用。

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY
Parkinson's Disease Pub Date : 2023-10-23 eCollection Date: 2023-01-01 DOI:10.1155/2023/5016802
José Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Robert Fekete
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引用次数: 0

摘要

背景:在帕金森病患者中,从椅子上站起来或从坐到站(STS)的任务经常受到损害。这些患者通常将这种困难归因于下肢无力。然而,肌肉力量在STS转移任务中的作用尚未完全阐明。目的:我们旨在确定肌肉力量在STS任务中的作用。方法:我们研究了90例PD患者和52例性别和年龄匹配的对照组。通过临床检查,使用医学研究委员会量表、测力仪(腿部弯曲)和称重机(腿部压力)测量双腿的下肢力量。询问患者是否存在主观下肢无力或相关感觉。结果:STS任务异常20例(22.2%)(MDS-UPDRS-III第3.9项≥2分)。这些患者的改良Hoehn和Yahr分期较高(P  <  0.001)和较高的MDS-UPDRS运动总分(P  <  0.001),与70名具有正常STS任务的PD患者相比。与STS任务正常和对照组正常的PD患者相比,STS任务异常的患者更频繁地表现出下肢无力,并且近端下肢肌肉力量较低。感知到的下肢无力增加了异常STS任务的风险,OR:11.93(95%CI 1.51-9.432),而髋关节伸展强度≤9 公斤/压力也增加了STS任务异常的风险,OR:4.45(95%CI 1.49-13.23)。在多变量回归分析中,运动迟缓和髋关节力量下降与STS任务异常有关。结论:与帕金森病和STS任务正常的患者相比,帕金森病和异常STS任务的患者更常见地抱怨下肢无力,并且近端下肢力量下降,这可能导致STS任务的异常。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Role of Muscle Strength in the Sit-to-Stand Task in Parkinson's Disease.

The Role of Muscle Strength in the Sit-to-Stand Task in Parkinson's Disease.

Background: Rising from a chair or the sit-to-stand (STS) task is frequently impaired in individuals with Parkinson's disease (PD). These patients commonly attribute such difficulties to weakness in the lower extremities. However, the role of muscle strength in the STS transfer task has not been fully elucidated.

Objective: We aim at determining the role of muscle strength in the STS task.

Methods: We studied 90 consecutive patients with PD and 52 sex- and age-matched controls. Lower limb strength was determined in both legs by clinical examination using the Medical Research Council Scale, dynamometric (leg flexion) and weighting machine (leg pressure) measures. Patients were interrogated regarding the presence of subjective lower limb weakness or allied sensations.

Results: There were 20 patients (22.2%) with abnormal STS task (item 3.9 of the MDS-UPDRS-III ≥2 points). These patients had higher modified Hoehn and Yahr stage (P  <  0.001) and higher total motor scores of the MDS-UPDRS(P  <  0.001), compared with 70 PD patients with normal STS task. Patients with abnormal STS task endorsed lower limb weakness more frequently and had lower muscle strength in the proximal lower extremities, compared to PD patients with normal STS task and normal controls. The presence of perceived lower limb weakness increased the risk of an abnormal STS task, OR: 11.93 (95% C.I. 1.51-94.32), whereas a hip extension strength ≤9 kg/pressure also increased the risk of abnormal STS task, OR: 4.45 (95% C.I. 1.49-13.23). In the multivariate regression analysis, bradykinesia and decreased hip strength were related to abnormal STS task.

Conclusions: Patients with PD and abnormal STS task complain more commonly of lower limb weakness and have decreased proximal lower limb strength compared to patients with PD and normal STS task, likely contributing to abnormalities in performing the STS task.

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来源期刊
Parkinson's Disease
Parkinson's Disease CLINICAL NEUROLOGY-
CiteScore
5.80
自引率
3.10%
发文量
0
审稿时长
18 weeks
期刊介绍: Parkinson’s Disease is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the epidemiology, etiology, pathogenesis, genetics, cellular, molecular and neurophysiology, as well as the diagnosis and treatment of Parkinson’s disease.
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