评估化学品暴露如何影响人类健康。

IF 0.8 4区化学 Q4 CHEMISTRY, ANALYTICAL

LC GC Europe Pub Date : 2023-06-01

Erin S Baker

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引用次数: 0

摘要

由于我们日常生活中遇到的人为分子的范围和数量，以及它们在全身的复杂转变，测量化学暴露是极具挑战性的。为了广泛描述化学暴露如何影响人类健康，必须结合基因组、转录组、蛋白质组、内源性代谢组和外源性测量。然而，尽管基因组、转录组学和蛋白质组学分析在过去二十年中取得了快速进展，但在非靶向外源性和内源性小分子测量的仪器和计算方面仍然非常需要进步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Assessing How Chemical Exposures Affect Human Health.

Measuring chemical exposure is extremely challenging due to the range and number of anthropogenic molecules encountered in our daily lives, as well as their complex transformations throughout the body. To broadly characterize how chemical exposures influence human health, a combination of genomic, transcriptomic, proteomic, endogenous metabolomic, and xenobiotic measurements must be performed. However, while genomic, transcriptomic, and proteomic analyses have rapidly progressed over the last two decades, advancements in instrumentation and computations for nontargeted xenobiotic and endogenous small molecule measurements are still greatly needed.

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来源期刊

LC GC Europe 化学-分析化学

CiteScore

0.37

自引率

60.00%

发文量

审稿时长

3 months

期刊介绍： Because LCGC is directed to experienced researchers and applications personnel in the field of chromatography, avoid describing details or techniques that are common knowledge among such specialists.