狗对甲氧苄啶-磺胺甲恶唑和阿莫西林-克拉维酸同时发生超敏反应。

IF 1.5 3区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Science Pub Date : 2023-11-01 Epub Date: 2023-10-04 DOI:10.4142/jvs.23188

Yunho Jeong, Yoon-Hwan Kim, Jin-Ok Ahn, Jin-Young Chung

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引用次数: 0

摘要

众所周知，抗生素能够通过各种机制引起超敏反应。我们报告了一例药物诱导的免疫性血小板减少症（DITP）和过敏性休克在狗服用两类抗生素后同时发生，即甲氧苄啶-磺胺甲恶唑（TMP-SMX）和阿莫西林-克拉维酸盐（AMC）。患者在停用TMP-SMX后完全从DITP中恢复，AMC引起的过敏性休克接受重症监护治疗。DITP是一种罕见的药物不良反应（ADR），过敏性休克是一种危及生命的ADR。这是第一例狗因两种抗生素引起两种类型的超敏反应的病例报告。

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Simultaneous hypersensitivity reactions to trimethoprim-sulfamethoxazole and amoxicillin-clavulanate in a dog.

Antibiotics are known to be able to cause hypersensitivity reactions through various mechanisms. We present a case of drug-induced immune thrombocytopenia (DITP) and anaphylactic shock occurring simultaneously in a dog after the administration of two classes of antibiotics, namely trimethoprim-sulfamethoxazole (TMP-SMX) and amoxicillin-clavulanate (AMC). The patient recovered completely from DITP on discontinuation of TMP-SMX and the anaphylactic shock caused by AMC was treated with intensive care. DITP is a rare adverse drug reaction (ADR), and anaphylactic shock is a life-threatening ADR. This is the first case report of a dog manifesting two types of hypersensitivity reactions caused by two antibiotics.

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来源期刊

Journal of Veterinary Science 农林科学-兽医学

CiteScore

3.10

自引率

5.60%

发文量

审稿时长

1.3 months

期刊介绍： The Journal of Veterinary Science (J Vet Sci) is devoted to the advancement and dissemination of scientific knowledge concerning veterinary sciences and related academic disciplines. It is an international journal indexed in the Thomson Scientific Web of Science, SCI-EXPANDED, Sci Search, BIOSIS Previews, Biological Abstracts, Focus on: Veterinary Science & Medicine, Zoological Record, PubMed /MEDLINE, Index Medicus, Pubmed Central, CAB Abstracts / Index Veterinarius, EBSCO, AGRIS and AGRICOLA. This journal published in English by the Korean Society of Veterinary Science (KSVS) being distributed worldwide.