{"title":"静脉给药期间药物浓度水平的随机模型","authors":"I. Dzhalladova, Miroslava R��i�kov�","doi":"10.7494/opmath.2022.42.6.833","DOIUrl":null,"url":null,"abstract":"A stochastic model describing the concentration of the drug in the body during its IV-administration is discussed. The paper compares a deterministic model created with certain simplifications with the stochastic model. Fluctuating and irregular patterns of plasma concentrations of some drugs observed during intravenous infusion are explained. An illustrative example is given with certain values of drug infusion rate and drug elimination rate.","PeriodicalId":45563,"journal":{"name":"Opuscula Mathematica","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stochastic model of drug concentration level during IV-administration\",\"authors\":\"I. Dzhalladova, Miroslava R��i�kov�\",\"doi\":\"10.7494/opmath.2022.42.6.833\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A stochastic model describing the concentration of the drug in the body during its IV-administration is discussed. The paper compares a deterministic model created with certain simplifications with the stochastic model. Fluctuating and irregular patterns of plasma concentrations of some drugs observed during intravenous infusion are explained. An illustrative example is given with certain values of drug infusion rate and drug elimination rate.\",\"PeriodicalId\":45563,\"journal\":{\"name\":\"Opuscula Mathematica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Opuscula Mathematica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7494/opmath.2022.42.6.833\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATHEMATICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Opuscula Mathematica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7494/opmath.2022.42.6.833","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICS","Score":null,"Total":0}
Stochastic model of drug concentration level during IV-administration
A stochastic model describing the concentration of the drug in the body during its IV-administration is discussed. The paper compares a deterministic model created with certain simplifications with the stochastic model. Fluctuating and irregular patterns of plasma concentrations of some drugs observed during intravenous infusion are explained. An illustrative example is given with certain values of drug infusion rate and drug elimination rate.