抗坏血酸降低造影剂肾病发展的疗效

Razavi International Journal of Medicine Pub Date : 2016-11-19 DOI:10.5812/RIJM.37341

H. Naghavi, S. Amini

{"title":"抗坏血酸降低造影剂肾病发展的疗效","authors":"H. Naghavi, S. Amini","doi":"10.5812/RIJM.37341","DOIUrl":null,"url":null,"abstract":"Introduction: To assess the beneﬁts of prophylactic ascorbic acid to reduce development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary interventions (PCIs). Methods: PubMed was searched with the search strategy of (vitamin C OR ascorbic acid) AND (kidney OR renal) AND (PCI OR percutaneous coronary Intervention OR cardiac OR heart). There was no date and language restriction for the selection of the articles. All the randomized controlled trials (RCTs) which investigated the eﬃcacy of AA on reducing the incidence of CIN were included. Totally 267 articles were found at the initial search; however, only 10 RCTs were eligible to be included. Odds ratio is presented for each of the articles as the eﬀect size. Conclusions: Controversial ﬁndings were reported on the eﬃcacy of AA on reducing the CIN development; due to various limitations of these articles, there is still great debate among the cardiology and radiology communities, which increases the need for further researches.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Efficacy of Ascorbic Acid on Reducing the Development of Contrast-Induced Nephropathy\",\"authors\":\"H. Naghavi, S. Amini\",\"doi\":\"10.5812/RIJM.37341\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: To assess the beneﬁts of prophylactic ascorbic acid to reduce development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary interventions (PCIs). Methods: PubMed was searched with the search strategy of (vitamin C OR ascorbic acid) AND (kidney OR renal) AND (PCI OR percutaneous coronary Intervention OR cardiac OR heart). There was no date and language restriction for the selection of the articles. All the randomized controlled trials (RCTs) which investigated the eﬃcacy of AA on reducing the incidence of CIN were included. Totally 267 articles were found at the initial search; however, only 10 RCTs were eligible to be included. Odds ratio is presented for each of the articles as the eﬀect size. Conclusions: Controversial ﬁndings were reported on the eﬃcacy of AA on reducing the CIN development; due to various limitations of these articles, there is still great debate among the cardiology and radiology communities, which increases the need for further researches.\",\"PeriodicalId\":20994,\"journal\":{\"name\":\"Razavi International Journal of Medicine\",\"volume\":\"5 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Razavi International Journal of Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5812/RIJM.37341\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Razavi International Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/RIJM.37341","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

摘要

前言:评估预防性抗坏血酸对减少经皮冠状动脉介入治疗(pci)患者造影剂肾病(CIN)发展的益处。方法:以(维生素C或抗坏血酸)、(肾脏或肾脏)和(PCI或经皮冠状动脉介入治疗或心脏或心脏)为检索策略进行PubMed检索。文章的选择没有日期和语言限制。所有研究AA降低CIN发生率的随机对照试验(RCTs)均被纳入。首次检索共检索到267篇文章;然而，只有10项rct符合纳入条件。每一篇文章的优势比作为效应大小。结论:关于AA是否能降低CIN的发生存在争议;由于这些文章的各种局限性，在心脏病学和放射学界仍然存在很大的争论，这增加了进一步研究的需要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Efficacy of Ascorbic Acid on Reducing the Development of Contrast-Induced Nephropathy

Introduction: To assess the beneﬁts of prophylactic ascorbic acid to reduce development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary interventions (PCIs). Methods: PubMed was searched with the search strategy of (vitamin C OR ascorbic acid) AND (kidney OR renal) AND (PCI OR percutaneous coronary Intervention OR cardiac OR heart). There was no date and language restriction for the selection of the articles. All the randomized controlled trials (RCTs) which investigated the eﬃcacy of AA on reducing the incidence of CIN were included. Totally 267 articles were found at the initial search; however, only 10 RCTs were eligible to be included. Odds ratio is presented for each of the articles as the eﬀect size. Conclusions: Controversial ﬁndings were reported on the eﬃcacy of AA on reducing the CIN development; due to various limitations of these articles, there is still great debate among the cardiology and radiology communities, which increases the need for further researches.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Razavi International Journal of Medicine

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Razavi International Journal of Medicine aims at publishing the high quality materials, both clinical and scientific, on all aspects of Medicine and medical sciences. The Razavi International Journal of Medicine is an international, English language, peer-reviewed, open access, free access journal dealing with general Medicine and medical sciences, clinical and basic studies, public health, Disaster Medicine and Health Policy. It is an official Journal of the education and research department, Razavi Hospital and is published quarterly.