预防细支气管炎从医院到家庭:环境和药理学策略

IF 0.3 Q4 PEDIATRICS
A. Dotta
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引用次数: 1

摘要

毛细支气管炎是婴幼儿死亡和发病的主要原因之一,高危婴儿出生后1年的住院率在流行季节较高。除了水合和高渗盐水外,没有特定的治疗方法证明有效。轻度形式可以在门诊治疗,避免无用的住院治疗。环境预防在医院环境、门诊门诊和家庭环境中至关重要:为此目的,必须向家庭和照料者强调手卫生、烟草接触、母乳喂养。药理学预防使用人源化单克隆抗体(帕利珠单抗),该抗体显示可有效降低< 35孕周的早产儿、支气管肺发育不良婴儿和先天性心脏病婴儿的住院率。在过去的2年中,不同的建议和指南证实了帕利珠单抗预防的重要性,但基于不同医疗保健系统的群体和社会之间存在一些差异。在任何情况下,重要的是医院和这些患者的所有护理人员之间的良好联系,以减少病毒暴露,提高高危患者的防御能力。第11届国际新生儿学与卫星会议会议记录·卡利亚里(意大利)·2015年10月26日-31日·从子宫到成人客座编辑:Vassilios Fanos(意大利卡利亚里),Michele Mussap(意大利热那亚),Antonio Del Vecchio(意大利巴里),Bo Sun(中国上海),Dorret I. Boomsma(荷兰阿姆斯特丹),Gavino Faa(意大利卡利亚里),Antonio Giordano(美国费城)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevention of bronchiolitis from the hospital to home: enviromental and pharmacological strategies
Bronchiolitis is one of the major cause of mortality and morbidity during infancy, with high hospitalization rate during epidemic season for high risk infants during the first year of life. There is no specific therapy with proven efficacy apart hydration and hypertonic saline. Mild forms can be treated in outpatient setting avoiding a useless hospitalization. Enviromental prevention is crucial in hospital setting, in outpatient ambulatory and at home: for this purpose hand hygiene, tobacco exposure, breastfeeding must be emphasized with families and caregivers. Pharmacological prophylaxis uses a humanized monoclonal antibody (palivizumab) shown effective in reducing hospitalization rate in preterm infants < 35 weeks gestational age, infants with bronchopulmonary dysplasia and infants with congenital heart disease. During the last 2 years different recommandations and guidelines confirmed the importance of prophylaxis with palivizumab with some differences between Groups and Societies based on different healthcare systems. In any case it is important a good contact between hospital and all caregivers of these patients to reduce the viral exposure and increase the defense capability of high risk patients. Proceedings of the 11 th International Workshop on Neonatology and Satellite Meetings · Cagliari (Italy) · October 26 th -31 st , 2015 · From the womb to the adult Guest Editors: Vassilios Fanos (Cagliari, Italy), Michele Mussap (Genoa, Italy), Antonio Del Vecchio (Bari, Italy), Bo Sun (Shanghai, China), Dorret I. Boomsma (Amsterdam, the Netherlands), Gavino Faa (Cagliari, Italy), Antonio Giordano (Philadelphia, USA)
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来源期刊
CiteScore
1.00
自引率
25.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) is a peer-reviewed interdisciplinary journal which provides a forum on new perspectives in pediatric and neonatal medicine. The aim is to discuss and to bring readers up to date on the latest in research and clinical pediatrics and neonatology. Special emphasis is on developmental origin of health and disease or perinatal programming and on the so-called ‘-omic’ sciences. Systems medicine blazes a revolutionary trail from reductionist to holistic medicine, from descriptive medicine to predictive medicine, from an epidemiological perspective to a personalized approach. The journal will be relevance to clinicians and researchers concerned with personalized care for the newborn and child. Also medical humanities will be considered in a tailored way. Article submission (original research, review papers, invited editorials and clinical cases) will be considered in the following fields: fetal medicine, perinatology, neonatology, pediatrics, developmental programming, psychology and medical humanities.
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