马哈拉施特拉邦西部Sangli地区血小板减少症的临床病理谱-横断面研究

Sheetal Maheshkumar Sale, I. Bansal, V. Mane, D. Mane
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引用次数: 0

摘要

前言:血小板减少症是目前常见的血液学发现与各种病因是有低血小板计数的情况。血小板减少症的病因是多因素的,这使得治疗具有挑战性。目的:研究印度马哈拉施特拉邦Sangli地区人群血小板减少症的临床病理谱。材料和方法:在印度马哈拉施特拉邦Sangli区的一家三级保健中心进行了一项横断面研究,为期两年,从2019年7月到2021年6月。该研究包括920例血小板计数< 15万/mm3的患者,不论其年龄组。对血小板计数小于15万/mm3的患者的临床特征、实验室数据和并发症进行了分析和制表。所有收集到的数据在MS-Excel中制表,并在社会科学统计软件包(SPSS) 20.0版本中进行分析,其中使用频率分布检验研究变量。结果:总样本量920例,其中男性546例(59.35%),女性374例(40.65%)。在920例患者中,大多数392例(42.61%)被诊断患有导致血小板减少的感染,其中登革热被确定为最常见的原因,有173例(18.80%),其次是其他感染和其他疾病。结论:登革热是本研究中最常见的导致血小板减少的传染病。目前的研究可能有助于分类感染水平,即轻度或重度血小板减少症。出血的早期迹象可以阻止进一步的并发症和转化为高风险的不同发病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinicopathological Spectrum of Thrombocytopenia in Sangli District of Western Maharashtra- A Cross-sectional Study
Introduction: Thrombocytopenia is now a day’s common haematological finding with various aetiologies is the situation where there is low blood platelet count. Aetiology for thrombocytopenia is multi factorial which makes the management challenging. Aim: To study the clinicopathological spectrum of thrombocytopenia in population of Sangli district, Maharashtra, India. Materials and Methods: A cross-sectional study was conducted in a tertiary care centre in Sangli district, Maharashtra, India, for a period of two years from July 2019 to June 2021. It included 920 patients with platelet count<1.5 lakh/mm3 irrespective of their age group. The clinical profile laboratory data and complications of patients with a platelet count of less than 1,50,000/mm3 were analysed and tabulated. All the collected data was tabulated in MS-Excel and analysed in Statistical Package for the Social Sciences (SPSS) version 20.0 where frequency distribution was used test study variables. Results: The total sample size was 920 with 546 (59.35%) males and 374 (40.65%) females. Out of 920 patients, majority 392 (42.61%) were diagnosed with infections that lead to thrombocytopenia where dengue was identified as the most common cause having 173 (18.80%) cases followed by other infection and other diseases. Conclusion: Dengue was observed to be the most common infectious disease causing thrombocytopenia in this study. The present study might help in categorising the level of infection i.e., mild or severe thrombocytopenia. Early signs of bleeding could stop further complications and transformation into high risk towards different morbidities respectively.
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