益生菌能战胜环境内分泌干扰物吗?

Q4 Pharmacology, Toxicology and Pharmaceutics
Çiğdem Sevİm, M. Kara
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引用次数: 1

摘要

对内分泌系统有负面影响的化合物被称为内分泌干扰化合物(EDCs)。有几种不同类型的化合物,在环境中有几种不同的使用领域,它们可以被归类为EDCs。这些化学物质对生物体的健康有广泛的负面影响,这取决于它们的目标激素系统。EDCs是科学研究中最受欢迎的主题之一,因为它们被广泛使用,生物体经常暴露于这些化学物质。EDCs有多种接触途径,如口服、吸入和皮肤接触。对羟基苯甲酸酯、酚类化合物、邻苯二甲酸酯和杀虫剂是最常见的EDCs。目前,肠道微生物的分布、益生菌以及调节这些微生物的食品补充剂及其对各种有害化学物质的保护作用引起了人们的关注。因此,在这一领域进行了许多研究,并根据这些研究的结果制定了某些饮食计划。事实上,为了减少和消除有害化学物质的负面影响,并确保生物体在这些条件下产生强烈的反应,益生菌是首选。在本文中,我们将重点介绍EDCs及其对健康的影响以及益生菌对EDCs暴露条件的积极影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Can probiotics win the battle against environmental endocrine disruptors?
Compounds that have negative effects on the endocrine system are called endocrine disrupting compounds (EDCs). There are several different types of compounds, with several different usage areas in the environment, which can be classified as EDCs. These chemicals have a wide range of negative health effects in organisms, depending on their target hormone system. EDCs are among the most popular topics of scientific research, as they are widely used and organisms are frequently exposed to these chemicals. There are various exposure routes for EDCs, such as oral, inhalation and dermal exposure. Parabens, phenolic compounds, phthalates, and pesticides are the most common EDCs. Nowadays, intestinal microorganism distribution, probiotics, and food supplements that regulate these microorganisms and their protective effects against various harmful chemicals attract attention. For this reason, many studies have been carried out in this field and certain diet schemes have been created according to the results of these studies. In fact, probiotics are preferred in order to reduce and eliminate the negative effects of harmful chemicals and to ensure that the organism reacts strongly in these conditions. In this review, we will focus on EDCs, their health effects and positive effects of probiotics on EDCs exposure conditions.
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来源期刊
Arhiv za Farmaciju
Arhiv za Farmaciju Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
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发文量
19
审稿时长
12 weeks
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