乳腺良恶性肿瘤中亲银核仁组织区参数的比较评价

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
M. Koksal, S. Doğan, R. Eroz, F. Ozturk, A. Ozturk, N. Cucer
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引用次数: 1

摘要

的目标。本文的目的是通过AgNOR总面积/核面积(TAA/NA)的新方法来评价AgNOR参数对乳腺良恶性肿瘤的鉴别作用。材料和方法。研究分为对照组(n = 14)、良性组(n = 18)和恶性组(n = 28)。采用AgNOR染色技术,评估平均AgNOR数和TAA/NA比值。结果。正常组与患者组AgNOR数比较差异有统计学意义(p < 0.001),恶性组与良性组平均AgNOR数比较差异无统计学意义(p < 0.05)。TAA/NA比值,对照组与良性组(p < 0.001)、对照组与恶性组(p < 0.001)、恶性组与良性组差异均有统计学意义。(p < 0.05)。结论。我们认为TAA/NA率的评估,与AgNOR数相比,可以更敏感和有用的工具来区分乳腺良恶性病变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative evaluation of argyrophilic nucleolar organizer regions parameters in benign and malignant breast tumors
Aim. The aim of the paper was to evaluate the AgNOR parameters for the discrimination of benign from malignant breast tumors via a new approach - the total AgNOR area/nuclear area (TAA/NA). Material and methods. Three groups, consisting of control (n = 14), benign (n = 18) and malignant (n = 28) participants were included in the study. The AgNOR staining technique was performed and both mean AgNOR number and TAA/NA ratio were evaluated. Results. While the differences between the control and patient groups were statistically significant for AgNOR number (p < 0.001), it was not significant between the malignant group and the benign group for mean AgNOR number (p > 0.05). For the ratio of TAA/NA, the differences between the control and benign group (p < 0.001), control and malignant group (p < 0.001), and malignant and benign patient groups were significant. (p < 0.05). Conclusion. We consider that the evaluation of the TAA/NA rate, when compared with the AgNOR number, can be more sensitive and useful tool for distinguishing benign from the malignant breast lesions.
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来源期刊
Acta Facultatis Medicae Naissensis
Acta Facultatis Medicae Naissensis MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
0.00%
发文量
13
审稿时长
12 weeks
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