与急性胰腺炎患者致命结局相关的临床和简单实验室数据

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
T. Formanchuk, V. Shaprinskiy, A. Formanchuk
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引用次数: 0

摘要

目标该研究的目的是评估急性胰腺炎死亡率与入院当天收到的临床和简单实验室数据的关系。患者和方法。我们回顾性分析了99例中重度急性胰腺炎患者的临床和实验室参数。所有患者分为两组:死者和幸存者。结果。我们没有发现两组在年龄和性别分布上有显著差异。然而,发现急性胰腺炎的主要病因是酒精、患者早期住院(发病后6小时)以及死亡组中坏死性感染类型的数量。两组间的伴随病理无显著差异。死亡组的并发症总数明显高于存活组,分别为21例(100%)和42例(53.8%)(p = 0.0001)。入院当天测定的实验室参数中,死亡组刺扎率显著升高至19.8±9.8,ESR显著升高,AST显著升高至225.3±47.5 U/L,尿素显著升高至11.2±7.7 mmol/L,肌酐显著升高至173.6±26.1 mmol/L。结论。酒精性急性胰腺炎、坏死性感染型胰腺炎症、晚期并发症和合并症的发生率在死亡组中明显较高。入院时测定的stab、ESR、AST、尿素和肌酐水平在死亡组中明显占主导地位,这对于预测急性胰腺炎的死亡率需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical and simple laboratory data associated with fatal outcomes in patients with acute pancreatitis
Aims. The aim of the study was to evaluate the association of mortality in acute pancreatitis with clinical and simple laboratory data received on the day of admission. Patients and methods. In our retrospective study, the clinical and laboratory parameters of 99 patients with moderate and severe acute pancreatitis were analyzed. All patients were divided into two groups: deceased and survivors. Results. We did not find a significant difference in age and gender distribution between the comparison groups. However, a significant predominance of alcoholic etiology of acute pancreatitis, early hospitalization (up to 6 hours from the onset of the disease) of patients, and the number of necrotizing infected type in the deceased group were found. Concomitant pathology did not significantly differ in comparison groups. In patients from the deceased group, the total number of all complications was significantly higher than in the group of survivors-21 (100%) and 42 (53.8%) (p = 0.0001), respecting. Among the laboratory parameters determined on the day of admission, in the deceased group, there was a significant increase in stabs to 19.8 ± 9.8 and ESR, AST to 225.3 ± 47.5 U/L, urea to 11.2 ± 7.7 mmol/L, and creatinine to 173.6 ± 26.1 mmol/L. Conclusion. The alcoholic genesis of acute pancreatitis, necrotizing infected type of inflammation of the pancreas, presence of late complications, and comorbidities were significantly higher in the deceased group. The levels of stabs, ESR, AST, urea, and creatinine determined on the admission significantly dominated in the deceased group, which requires further study for the prediction of mortality of acute pancreatitis.
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来源期刊
Acta Facultatis Medicae Naissensis
Acta Facultatis Medicae Naissensis MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
0.00%
发文量
13
审稿时长
12 weeks
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