一种新的血液透析患者Covid-19评分系统:改进的早期预警评分

R. Stolić, Dragica Bukumiric, M. Jovanovic, T. Nikolić, Tatjana Labudović, V. Mitrović, Kristina Bulatovic, S. Sovtic, Dušica Miljković, Aleksandra Balović, Roksanda Krivčević, S. Jovanović
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引用次数: 0

摘要

介绍。在冠状病毒流行之初,关于血液透析患者是否有更高的冠状病毒感染风险以及哪些因素可能影响临床症状的严重程度,没有足够的数据。目标。本研究的目的是确定修正预警评估(MEWS)评分对评估冠状病毒疾病恶化的意义。方法。该研究是在塞尔维亚克拉古耶瓦茨大学临床中心的COVID透析中进行的,作为一项回顾性描述性分析研究,该中心专门组织治疗从血液透析中心“Ćuprija”转来的SARS-Cov-2感染阳性患者。监测的参数包括常规实验室检查结果、人口统计学和性别结构、动脉血压、合并症和残余利尿的存在、透析持续时间、肺部放射学评估、MEWS评分的测定。结果在入院和治疗结束时进行监测。结果。血清乳酸脱氢酶浓度(486±107.62∶423.7±92.4 U/L)差异有统计学意义;P = 0.022,绝对单核细胞计数(0.46±0.15∶0.67±0.34 × 103;P = 0.008)。MEWS评分也显著升高(b = 0.017;P = 0.030)。MEWS评分升高与年龄呈正相关(b = 0.027;P = 0.002)和伴发性高血压(b = 0.700;P = 0.033)。结论。观察期内,合并SARS-Cov-2感染的透析患者MEWS评分程度明显升高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
Introduction. At the very beginning of the Corona virus epidemic there was not enough data on whether hemodialysis patients have a higher risk for Corona virus infection and which factors may affect the severity of clinical picture. Objective. The aim of the study was to determine the significance of the Modified Early Warning Assessment (MEWS) score for the assessment of coronavirus disease exacerbation. Methods. The research was conducted in COVID dialysis, as a retrospective, descriptive-analytical study, at the University Clinical Center Kragujevac, Serbia, which was organized ad-hoc for treatment of SARS-Cov-2 infection positive patients, which are transfered from Center for Hemodialysis "Ćuprija". They were evaluated routine laboratory findings, demographic and gender structure, arterial blood pressure, presence of comorbidities and residual diuresis, duration of dialysis, radiological evaluation of lungs, determination of MEWS score were the parameters that were monitored. The results were monitored on admission and and in the end of treatment. Results. A statistically significant difference was registered in serum lactate dehydrogenase concentration (486 ± 107.62 vs. 423.7 ± 92.4 U/L); p = 0.022 and absolute monocyte count (0.46 ± 0.15 vs. 0.67 ± 0.34 x 103; p = 0.008). The significant increase in MEWS score was also found (b = 0.017; p = 0.030). There was a positive correlation between increase of MEWS score and age (b = 0.027; p = 0.002) and arterial hypertension as a concomitant comorbidity (b = 0.700; p = 0.033). Conclusion. In the observed period, there was a significant increase in the degree of MEWS score of dialysis patients who had SARS-Cov-2 infection.
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