原发性纵隔大b细胞淋巴瘤

Praxis Medica Pub Date : 2019-01-01 DOI:10.5937/PRAMED1901049K

S. Knežević, Z. I. Gajović, M. Petrović

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引用次数: 8

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Primary mediastinal large B-cell lymphoma

ESSENTIAL: ● Hematopathology review of all slides with at least one paraffin block or 15 unstained slides representative of the tumor. Rebiopsy if consult material is nondiagnostic. ● Adequate morphology and immunophenotyping to establish diagnosis ○ Paraffin Panel: CD3, CD20 and/or another pan-B-cell marker (CD19, PAX-5, CD79a) or ○ Flow cytometry immunophenotypic studies: CD54 (LCA), CD3, CD5, CD10, CD19, CD20, CD22, kappa and lambda light chains ● Additional immunohistochemical studies to determine subgroup: PD-L1/L2, CD5, CD10, CD15, CD23, CD54, CD79a, BCL-2, BCL-6, MUM-1/IRF4, and MIB1 (Ki67),

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来源期刊

Praxis Medica

自引率

0.00%

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审稿时长

4 weeks