Effects of Yiqi Fanggan Mixture on Anti-Stress Response and Immunity of Mice

To study the effect of Yiqi Fanggan Mixture on the anti-stress response and immunity of mice, a Chinese herbal compound (composed of some tonic Chinese medicine, including astragalus flavone, deep-fried atractylodes macrocephala koidz, fortune eupatorium herb, cyrtomium fortunei, white cardamom, windproof, dyers woad root, licorice, jobstears seed) was given to the mice for intragastric administration once a day for 2 weeks. Mice in each group are subjected to normal pressure hypoxia test, swimming test, cold resistance test and high temperature resistance test. Organ index and serum hemolysin content of mice were also monitored. The results indicated that the Yiqi Fanggan Mixture can improve the survival time of mice under the condition of normal pressure hypoxia; prolong the swimming time and high temperature resistance time of mice; reduce the death rate of mice under the low temperature condition; and improve the activity of serum hemolysin and organ index of mice. The results showed that Yiqi Fanggan Mixture could improve the ability of anti-stress response and immune ability in mice.