{"title":"蛋白质多功能性:原理和机制","authors":"J. Zaretsky, D. Wreschner","doi":"10.4137/TOG.S657","DOIUrl":null,"url":null,"abstract":"In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of multiple functions on a single gene product(s) are analyzed. The last part represents a number of examples showing that multifunctionality is a basic feature of biologically active proteins.","PeriodicalId":88783,"journal":{"name":"Translational oncogenomics","volume":"3 1","pages":"99 - 136"},"PeriodicalIF":0.0000,"publicationDate":"2008-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"Protein Multifunctionality: Principles and Mechanisms\",\"authors\":\"J. Zaretsky, D. Wreschner\",\"doi\":\"10.4137/TOG.S657\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of multiple functions on a single gene product(s) are analyzed. The last part represents a number of examples showing that multifunctionality is a basic feature of biologically active proteins.\",\"PeriodicalId\":88783,\"journal\":{\"name\":\"Translational oncogenomics\",\"volume\":\"3 1\",\"pages\":\"99 - 136\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-05-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Translational oncogenomics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4137/TOG.S657\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational oncogenomics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4137/TOG.S657","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Protein Multifunctionality: Principles and Mechanisms
In the review, the nature of protein multifunctionality is analyzed. In the first part of the review the principles of structural/functional organization of protein are discussed. In the second part, the main mechanisms involved in development of multiple functions on a single gene product(s) are analyzed. The last part represents a number of examples showing that multifunctionality is a basic feature of biologically active proteins.