一项随机双盲对照研究,评估varika椰子发油对脱发和头皮屑女性头发健康的功效和安全性

M. Kura, Arun Gupta, R. Srivastava, S. Luthra
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摘要

背景:脱发是一种令人紧张的经历,通常与自我价值降低的形象有关,女性比男性更多。头皮屑可能与脱发有关。目的:探讨瓦提卡浓缩椰子发油(VHO)对脱发、头皮屑女性头发健康的安全性和有效性。方法:在孟买jj医院皮肤科门诊进行为期8周的双盲对照研究。44名健康女性受试者,头发长度≥齐肩,有掉发和头皮屑症状,随机分为两组。一组的成员每周晚上用VHO按摩两次头皮,然后在早上用提供的中性洗发水洗头。对照组以类似的方式使用市场上销售的椰子油品牌。主要观察指标:VHO对头发脱落、头皮屑及头发光泽、黑度、粗糙度、抗拉强度等健康指标的影响。评估的次要结局是受试者的总体安全性。随访时间分别为第14、28、42、56天。结果:VHO对控制头发脱落、头皮屑、改善头发整体状况安全有效。临床发现VHO在控制头发脱落,头皮屑,提高头发的抗拉强度和头发的光泽,黑度和粗糙度方面优于椰子油。受试者和医生对治疗反应的整体评价也显示VHO的疗效优于椰子发油。在研究过程中,没有受试者表现出对任何研究产品的敏感性,也没有不良事件的报道。结论:瓦提卡浓缩椰子发油安全有效地控制了头发脱落和头皮屑,改善了头发的整体健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A randomized double blind controlled study evaluating efficacy & Safety of vatika enriched coconut hair oil on hair health in women with hair fall and dandruff
Background: Hair loss can be a stressful experience often associated with images of reduced self-worth, more in women than men. Dandruff may be associated with hair loss. Objective: To investigate the safety and efficacy of Vatika Enriched Coconut Hair Oil (VHO) on hair health in women with hair fall and dandruff. Methods: This was a double-blind, controlled study of 8 week duration conducted at Dermatology outpatient department of J.J. Hospital, Mumbai. Forty four (44) healthy female subjects with at least shoulder length hair and complaints of hair fall and dandruff were randomized equally into 2 groups. Members of one group massaged their scalps with VHO twice a week at night followed by washing the hair in morning with a supplied neutral shampoo. Control group used a marketed brand of coconut oil in a similar manner. Main Outcome Measures: Effect of VHO on hair fall, dandruff and hair health parameters such as shininess, blackness, roughness and tensile strength of hair. Secondary outcome assessed was overall subject safety. Subjects were followed up at days 14, 28, 42 and 56 days. Results: VHO was found safe and effective in controlling hair fall, dandruff and improving the overall condition of hair. VHO was found clinically better than coconut oil in controlling hair fall, dandruff, improving the tensile strength of hair and the shininess, blackness and roughness of hair. Global evaluation of therapeutic response by subjects and physician also showed a better efficacy of VHO than coconut hair oil. None of the subjects exhibited sensitivity to any of the study products and no adverse events were reported during the course of the study. Conclusions: Vatika Enriched Coconut Hair Oil is safe and effective in controlling hair fall and dandruff and improving the overall hair-health.
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