{"title":"疫苗开发和伦理侧边:Covid-19生物医学研究中的非人灵长类动物","authors":"Álex G. Segura","doi":"10.46516/inmaterial.v7.126","DOIUrl":null,"url":null,"abstract":"The current ethical paradigm avails the use of nonhuman animal for experiments in biomedical research. It is acknowledged as a practice with a considerable moral burden, and thus certain regulations have been established. The singularity of nonhuman primates (NHP) in terms of their cognitive and emotional complexity grants them a virtual status of personhood, and is reflected in a stricter legislation that allows nonetheless their use in certain cases. The pandemic brought by SARS-CoV-2 has rushed the classical drug development design, and NHP have been one of the species used to test novel therapies. In this study, a search of the characteristics of NHP and experimental techniques performed for COVID-19 vaccine development purposes will be used to ponder the costs and benefits of these practices. Under a critical eye, the results of these studies will be analyzed beyond the numbers, considering the harms for both human and NHP as well as the extension of the benefits.","PeriodicalId":33711,"journal":{"name":"Inmaterial","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Vaccine Development and Ethical Sidetracking: Nonhuman Primates in Covid-19 Biomedical Research\",\"authors\":\"Álex G. Segura\",\"doi\":\"10.46516/inmaterial.v7.126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The current ethical paradigm avails the use of nonhuman animal for experiments in biomedical research. It is acknowledged as a practice with a considerable moral burden, and thus certain regulations have been established. The singularity of nonhuman primates (NHP) in terms of their cognitive and emotional complexity grants them a virtual status of personhood, and is reflected in a stricter legislation that allows nonetheless their use in certain cases. The pandemic brought by SARS-CoV-2 has rushed the classical drug development design, and NHP have been one of the species used to test novel therapies. In this study, a search of the characteristics of NHP and experimental techniques performed for COVID-19 vaccine development purposes will be used to ponder the costs and benefits of these practices. Under a critical eye, the results of these studies will be analyzed beyond the numbers, considering the harms for both human and NHP as well as the extension of the benefits.\",\"PeriodicalId\":33711,\"journal\":{\"name\":\"Inmaterial\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Inmaterial\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46516/inmaterial.v7.126\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inmaterial","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46516/inmaterial.v7.126","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Vaccine Development and Ethical Sidetracking: Nonhuman Primates in Covid-19 Biomedical Research
The current ethical paradigm avails the use of nonhuman animal for experiments in biomedical research. It is acknowledged as a practice with a considerable moral burden, and thus certain regulations have been established. The singularity of nonhuman primates (NHP) in terms of their cognitive and emotional complexity grants them a virtual status of personhood, and is reflected in a stricter legislation that allows nonetheless their use in certain cases. The pandemic brought by SARS-CoV-2 has rushed the classical drug development design, and NHP have been one of the species used to test novel therapies. In this study, a search of the characteristics of NHP and experimental techniques performed for COVID-19 vaccine development purposes will be used to ponder the costs and benefits of these practices. Under a critical eye, the results of these studies will be analyzed beyond the numbers, considering the harms for both human and NHP as well as the extension of the benefits.