疫苗开发和伦理侧边:Covid-19生物医学研究中的非人灵长类动物

Álex G. Segura
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引用次数: 0

摘要

目前的伦理范式是利用非人类动物进行生物医学研究实验。它被认为是一种具有相当道德负担的做法,因此制定了某些规定。非人类灵长类动物(NHP)在认知和情感复杂性方面的独特性赋予了它们虚拟的人格地位,这反映在更严格的立法中,尽管如此,它们在某些情况下仍被允许使用。SARS-CoV-2带来的大流行冲击了经典的药物开发设计,而NHP已成为用于测试新疗法的物种之一。在本研究中,将对NHP的特征和为COVID-19疫苗开发目的而开展的实验技术进行搜索,以思考这些做法的成本和收益。在批判的眼光下,这些研究的结果将被超越数字进行分析,考虑到对人类和NHP的危害以及扩展的好处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vaccine Development and Ethical Sidetracking: Nonhuman Primates in Covid-19 Biomedical Research
The current ethical paradigm avails the use of nonhuman animal for experiments in biomedical research. It is acknowledged as a practice with a considerable moral burden, and thus certain regulations have been established. The singularity of nonhuman primates (NHP) in terms of their cognitive and emotional complexity grants them a virtual status of personhood, and is reflected in a stricter legislation that allows nonetheless their use in certain cases. The pandemic brought by SARS-CoV-2 has rushed the classical drug development design, and NHP have been one of the species used to test novel therapies. In this study, a search of the characteristics of NHP and experimental techniques performed for COVID-19 vaccine development purposes will be used to ponder the costs and benefits of these practices. Under a critical eye, the results of these studies will be analyzed beyond the numbers, considering the harms for both human and NHP as well as the extension of the benefits.
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CiteScore
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