{"title":"Survivin作为肿瘤预后和治疗生物标志物的研究进展","authors":"A. Ismail","doi":"10.4236/OJPATHOLOGY.2018.81002","DOIUrl":null,"url":null,"abstract":"Survivin is an antiapoptotic protein expressed in tumor cells that correlates with aggressiveness, prognosis and treatment. Objective: This review summarizes significance of survivin expression among different tumor types highlighting the potential value of survivin as an important biomarker that may have an impact on patient’s response to therapy with prognostic implications.","PeriodicalId":57444,"journal":{"name":"病理学期刊(英文)","volume":"47 1","pages":"15-23"},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"A Review on Survivin as a Prognostic and Therapeutic Cancer Biomarker\",\"authors\":\"A. Ismail\",\"doi\":\"10.4236/OJPATHOLOGY.2018.81002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Survivin is an antiapoptotic protein expressed in tumor cells that correlates with aggressiveness, prognosis and treatment. Objective: This review summarizes significance of survivin expression among different tumor types highlighting the potential value of survivin as an important biomarker that may have an impact on patient’s response to therapy with prognostic implications.\",\"PeriodicalId\":57444,\"journal\":{\"name\":\"病理学期刊(英文)\",\"volume\":\"47 1\",\"pages\":\"15-23\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"病理学期刊(英文)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4236/OJPATHOLOGY.2018.81002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"病理学期刊(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/OJPATHOLOGY.2018.81002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Review on Survivin as a Prognostic and Therapeutic Cancer Biomarker
Survivin is an antiapoptotic protein expressed in tumor cells that correlates with aggressiveness, prognosis and treatment. Objective: This review summarizes significance of survivin expression among different tumor types highlighting the potential value of survivin as an important biomarker that may have an impact on patient’s response to therapy with prognostic implications.