菲律宾综合医院收治的 COVID-19 慢性血液透析成人患者的阴性转阴时间--一项回顾性队列研究。

IF 3.9 3区 环境科学与生态学 Q1 ENGINEERING, CIVIL
Water Resources Management Pub Date : 2024-03-22 eCollection Date: 2024-01-01 DOI:10.47895/amp.vi0.6460
Kristine May F Valmoria, Paolo Nikolai H So, Elizabeth S Montemayor
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引用次数: 0

摘要

目的:在菲律宾,患有 COVID-19 的慢性血液透析患者尽管临床康复,但仍需住院治疗,因为大多数独立透析室都要求通过逆转录酶聚合酶链反应(RT-PCR)证明阴性转阴。本研究旨在确定菲律宾总医院(PGH)收治的感染COVID-19的慢性血液透析成人患者通过COVID-19 RT-PCR检测转阴所需的时间,并根据当地指南的建议,采用基于症状或时间的程序,最终确保在感染COVID-19的情况下仍能进行适当的血液透析,缩短隔离期,节约资源,尤其是在资源有限的情况下:这是一项回顾性队列研究,研究对象为 2020 年 3 月至 2021 年 2 月期间,通过 RT-PCR 诊断出感染 COVID-19 后入住 PGH 的所有慢性血液透析成人患者。研究采用描述性统计方法对数据进行总结:研究共纳入了90名在PGH住院并通过RT-PCR检测出COVID-19阳性的慢性血液透析患者。这些患者中的大多数(53.3%)为中度 COVID-19。从出现症状到临床康复的中位天数为14.5天。首次转阴的中位时间为 18 天。大多数患者在第二周时转为阴性。临床康复时间与转阴时间之间的相关系数为 0.214:结论:在确诊 COVID-19 后入住 PGH 的慢性血液透析成年患者中,阴性转阴时间长于临床康复时间,两者之间的相关性很弱。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Time to Negative Conversion among Adult COVID-19 Patients on Chronic Hemodialysis Admitted at the Philippine General Hospital - A Retrospective Cohort Study.

Objectives: In the Philippines, patients on chronic hemodialysis with COVID-19 remain admitted in hospitals despite clinical recovery because most free-standing dialysis units require proof of negative conversion via Reverse Transcriptase - Polymerase Chain Reaction (RT-PCR). This study aims to determine the time to negative conversion of COVID-19 RT-PCR testing among adult patients on chronic hemodialysis with COVID-19 admitted at the Philippine General Hospital (PGH) and bring insight in using the symptom or time-based procedure as recommended by local guideline, and ultimately, to ensure delivery of adequate hemodialysis despite being infected with COVID-19, shorten isolation period, and conserve resources especially in resource-limited settings.

Methods: This is a retrospective cohort study on all adult patients on chronic hemodialysis who were admitted in PGH after the diagnosis of COVID-19 by RT-PCR between March 2020 and February 2021. Descriptive statistics was used in summarizing the data.

Results: A total of 90 patients on chronic hemodialysis who tested positive for COVID-19 via RT-PCR admitted at PGH were included in the study. Most of these patients had moderate COVID-19 at 53.3%. The median number of days from onset of symptoms to clinical recovery was 14.5 days. The median time to first negative conversion was 18 days. Most of these patients had negative conversion at the second week. The correlation coefficient between time to clinical recovery and negative conversion was 0.214.

Conclusion: Among adult patients on chronic hemodialysis who were admitted in PGH after the diagnosis of COVID-19, the time to negative conversion was longer compared to the time to clinical recovery with a very weak correlation between the two.

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来源期刊
Water Resources Management
Water Resources Management 环境科学-工程:土木
CiteScore
7.40
自引率
16.30%
发文量
332
审稿时长
9 months
期刊介绍: Water Resources Management is an international, multidisciplinary forum for the publication of original contributions and the exchange of knowledge and experience on the management of water resources. In particular, the journal publishes contributions on water resources assessment, development, conservation and control, emphasizing policies and strategies. Contributions examine planning and design of water resource systems, and operation, maintenance and administration of water resource systems. Coverage extends to these closely related topics: water demand and consumption; applied surface and groundwater hydrology; water management techniques; simulation and modelling of water resource systems; forecasting and control of quantity and quality of water; economic and social aspects of water use; legislation and water resources protection. Water Resources Management is supported scientifically by the European Water Resources Association, a scientific and technical nonprofit-making European association.
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