Applications of Supercomputers in Sequence Analysis and Genome Annotation

In the modern era of science, bioinformatics play a critical role in unraveling the potential genetic causes of various diseases. Two of the most important areas of bioinformatics today, sequence analysis and genome annotation, are essential for the success of identifying the genes responsible for different diseases. These two emerging areas utilize highly intensive mathematical calculations in order to carry out the processes. Supercomputers facilitate such calculations in an efficient and time-saving manner generating high-throughput images. Thus, this chapter thoroughly discusses the applications of supercomputers in the areas of sequence analysis and genome annotation. This chapter also showcases sophisticated software and algorithms utilized by the two mentioned areas of bioinformatics.