自体输血前白细胞减少的临床研究

Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion Pub Date : 2004-11-10 DOI:10.3925/JJTC1958.50.704

T. Igari, H. Ohto, T. Ogata, K. Ikeda, Kaoru Sato, T. Takagi, K. Takeyama, Shigeo Aota, S. Kikuchi

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引用次数: 0

摘要

本研究的目的是确定在储存前减少自体血液中白细胞数量的功效。研究样本包括121名接受骨科手术的患者，并计划接受多达1200毫升的自体血液。将其分为保存前白细胞减少组和未减少组。术后比较患者体温、白细胞计数、红细胞计数及C反应蛋白(CRP)水平。121例患者中有13例因风湿病病因被排除在比较之外。结果显示白细胞减少组(n=46)和非减少组(n=62)之间的效率无显著差异。白细胞减少组术后48小时CRP水平略低于未减少组。自体血液储存前白细胞减少的益处仍有待阐明。

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CLINICAL TRIAL OF PRESTORAGE LEUKOCYTE REDUCTION FOR AUTOLOGOUS BLOOD TRANSFUSION

The goal of the present study was to determine the efficacy of reducing the number of leukocytes in autologous blood before storage. The study sample consisted of 121 patients undergoing orthopedic surgery and scheduled to receive up to 1, 200mL autologous blood. They were divided into prestorage leukocyte reduction and no-reduction groups. Body temperature, white blood cell counts, red blood cell counts, and C reactive protein (CRP) levels were compared after operation. Thirteen of 121 patients were excluded from comparison due to rheumatic etiology. Results showed no significant difference in efficiency between the leukocyte-reduced (n=46) and non-reduced (n=62) groups. The leukocyte reduction group showed slightly lower CRP levels for 48h after surgery than the noreduction group. The benefits of prestorage leukocyte reduction of autologous blood remains to be elucidated.

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Nihon Yuketsu Gakkai zasshi = Journal of the Japan Society of Blood Transfusion

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