Epstein-Barr病毒相关的食管胃交界及胃淋巴上皮瘤样癌1例报告及文献复习

E. Atağ, S. Kazaz, H. Semiz, I. T. Unek, S. Sarıoğlu, T. Yavuzşen
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引用次数: 3

摘要

一名63岁男性因2个月的吞咽困难病史入住我院。内窥镜检查发现一个从食管远端开始并延伸到心脏的ululvegetan肿瘤。病理检查活检显示一个上皮恶性肿瘤,没有进一步的分类。患者在奥沙利铂、5-氟尿嘧啶和白细胞素(FOLFOX)方案的新辅助化疗后接受了手术。术后病理分析显示高级别eb病毒相关的胃食管交界和胃淋巴上皮瘤样癌。术后,我们计划给予6个周期的FOLFOX方案作为辅助治疗。淋巴上皮瘤样胃癌是一种罕见的胃癌类型,具有明显的临床病理特征,男性多见,好发于贲门,淋巴细胞浸润,淋巴结转移发生率较低,预后较好。手术切除是最有效的治疗方式。有高危因素的患者可考虑化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epstein-Barr Virus Associated Lymphoepithelioma-Like Carcinoma of the Esophagogastric Junction and Stomach: A Case Report and Review of the Literature
A 63-year-old man was admitted to our hospital with 2 months history of dysphagia. Endoscopic examination revealed an ulserovegetan tumor starting from distal esophagus and extending to the cardia. Pathological examination of the biopsy revealed an epithelial malignant tumor without further classification. The patient underwent a surgery following neo-adjuvant chemotherapy with oxaliplatin, 5-fluorouracil and leucoverin (FOLFOX) regimen. Postoperative pathological analyses showed high grade EBV-associated lymphoepithelioma-like carcinoma of the gastroesophagial junction and stomach. After surgery, we planned to administered 6 cycles of FOLFOX regimen as an adjuvant treatment. Lymphoepithelioma-like gastric carcinoma is a rare type of gastric carcinoma and has distinct clinic-pathologic characteristics, including male predominance, preferential location in the gastric cardia, lymphocytic infiltration, a lower frequency of lymph node metastases and more favorable prognosis. Surgical resection is the most effective treatment modality. Chemotherapy may be considered for patients who have high risk factors.
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