Katerina Matheis, B. Fuchs, Katharina Lemmnitzer, R. Süss, Hans Griesinger, S. Minarik, M. Oberle, M. Schulz, J. Schiller
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Combining TLC Separation with MS Detection - A Revival of TLC
It is very likely that every natural scientist has at least heard about thin-layer chromatography (TLC) because its fundamentals are taught in all basic courses of chemistry and biochemistry. TLC is widely used in preparative organic chemistry for a first check of a reaction mixture to monitor how many different products were generated. One typical application in biochemistry is the separation of plant dyes; this is particularly simple because the analytes are coloured and, thus, no staining step is necessary.
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