Manasee Choudhury, Shamima Parbin, S. Pegu, S. Banik, P. J. Das
{"title":"家蚕本地寄主植物天然生物活性代谢物抗氧化和抗菌猪病的比较分析","authors":"Manasee Choudhury, Shamima Parbin, S. Pegu, S. Banik, P. J. Das","doi":"10.36468/pharmaceutical-sciences.1069","DOIUrl":null,"url":null,"abstract":"The present study explores the natural bioactive metabolites, antioxidant and antibacterial activities present in the host plants of Antheraea assamensis (muga silkworm) viz . Machilus bombycina (som), Litsea polyantha (sualu), Litsea salicifolia (dighloti) and Litsea citrata (mejankari). The methanolic extracts of leaves of these plants were screened for their phytochemical analysis and free radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl as the free radical. Phytochemical analysis revealed the presence of flavonoids, phenolic compounds, carotenoids, saponins, coumarins, terpenoids, tanins, cardiac glucosides and xanthoproteins in the said plants. The results of 2,2-diphenyl-1-picrylhydrazyl scavenging activity revealed Litsea polyantha to exhibit stronger antioxidant efficiency compared to the rest. Besides these, the plant extracts were investigated for their antibacterial assessment against Gram-positive Staphylococcus aureus and Streptococcus suis and Gram-negative Pasteurella multocida and Escherichia coli bacteria found in pig. All the plant extracts were validated to possess antibacterial activity with variable potency. Litsea citrata was the most effective extract retarding microbial growth of both Gram-positive and Gram-negative bacteria, followed by Litsea salicifolia , Litsea polyantha and Machilus bombycina . The present findings underscore the fact that indigenous food plants of muga silkworm are fortified with antioxidant and antibacterial efficiency, which might pave to the development of novel herbal pharmacological compounds for the medication of pig diseases.","PeriodicalId":13292,"journal":{"name":"Indian Journal of Pharmaceutical Sciences","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative Analysis of Natural Bioactive Metabolites of the Indigenous Host Plants of Muga Silkworm for Antioxidant and Antibacterial Properties against Swine Diseases\",\"authors\":\"Manasee Choudhury, Shamima Parbin, S. Pegu, S. Banik, P. J. Das\",\"doi\":\"10.36468/pharmaceutical-sciences.1069\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The present study explores the natural bioactive metabolites, antioxidant and antibacterial activities present in the host plants of Antheraea assamensis (muga silkworm) viz . Machilus bombycina (som), Litsea polyantha (sualu), Litsea salicifolia (dighloti) and Litsea citrata (mejankari). The methanolic extracts of leaves of these plants were screened for their phytochemical analysis and free radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl as the free radical. Phytochemical analysis revealed the presence of flavonoids, phenolic compounds, carotenoids, saponins, coumarins, terpenoids, tanins, cardiac glucosides and xanthoproteins in the said plants. The results of 2,2-diphenyl-1-picrylhydrazyl scavenging activity revealed Litsea polyantha to exhibit stronger antioxidant efficiency compared to the rest. Besides these, the plant extracts were investigated for their antibacterial assessment against Gram-positive Staphylococcus aureus and Streptococcus suis and Gram-negative Pasteurella multocida and Escherichia coli bacteria found in pig. All the plant extracts were validated to possess antibacterial activity with variable potency. Litsea citrata was the most effective extract retarding microbial growth of both Gram-positive and Gram-negative bacteria, followed by Litsea salicifolia , Litsea polyantha and Machilus bombycina . The present findings underscore the fact that indigenous food plants of muga silkworm are fortified with antioxidant and antibacterial efficiency, which might pave to the development of novel herbal pharmacological compounds for the medication of pig diseases.\",\"PeriodicalId\":13292,\"journal\":{\"name\":\"Indian Journal of Pharmaceutical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.36468/pharmaceutical-sciences.1069\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Pharmaceutical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.36468/pharmaceutical-sciences.1069","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Comparative Analysis of Natural Bioactive Metabolites of the Indigenous Host Plants of Muga Silkworm for Antioxidant and Antibacterial Properties against Swine Diseases
The present study explores the natural bioactive metabolites, antioxidant and antibacterial activities present in the host plants of Antheraea assamensis (muga silkworm) viz . Machilus bombycina (som), Litsea polyantha (sualu), Litsea salicifolia (dighloti) and Litsea citrata (mejankari). The methanolic extracts of leaves of these plants were screened for their phytochemical analysis and free radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl as the free radical. Phytochemical analysis revealed the presence of flavonoids, phenolic compounds, carotenoids, saponins, coumarins, terpenoids, tanins, cardiac glucosides and xanthoproteins in the said plants. The results of 2,2-diphenyl-1-picrylhydrazyl scavenging activity revealed Litsea polyantha to exhibit stronger antioxidant efficiency compared to the rest. Besides these, the plant extracts were investigated for their antibacterial assessment against Gram-positive Staphylococcus aureus and Streptococcus suis and Gram-negative Pasteurella multocida and Escherichia coli bacteria found in pig. All the plant extracts were validated to possess antibacterial activity with variable potency. Litsea citrata was the most effective extract retarding microbial growth of both Gram-positive and Gram-negative bacteria, followed by Litsea salicifolia , Litsea polyantha and Machilus bombycina . The present findings underscore the fact that indigenous food plants of muga silkworm are fortified with antioxidant and antibacterial efficiency, which might pave to the development of novel herbal pharmacological compounds for the medication of pig diseases.
期刊介绍:
The Indian Journal of Pharmaceutical Sciences (IJPS) is a bi-monthly Journal, which publishes original research work that contributes significantly to further the scientific knowledge in Pharmaceutical Sciences (Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Therapeutics, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Pharmacovigilance, Pharmacoepidemiology, Pharmacoeconomics, Drug Information, Patient Counselling, Adverse Drug Reactions Monitoring, Medication Errors, Medication Optimization, Medication Therapy Management, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest). The Journal publishes original research work either as a Full Research Paper or as a Short Communication. Review Articles on current topics in Pharmaceutical Sciences are also considered for publication by the Journal.