PERSONIFICATION OF INTENSIVE THERAPY FOR ISCHEMIC CEREBRAL STROKE DEPENDING ON THE SEVERITY OF ENERGY STRUCTURAL DISORDERS

The aim of the work was to develop criteria for the severity of ischemic cerebral stroke (ICS) and the use of personalized intensive therapy (IT) technologies in the acute and acute periods of the disease. The clinical study included 108 patients with IMI (mean age 73,47±0,48 years). Based on the severity of energy structural disorders and personalized IT methods, all patients were divided into 4 groups. The first group consisted of patients with eubiotic energy structural status (ESST), who received personalized IT with homeostasis technologies. The following three groups consisted of patients with hypoergic ESST disorders: hypoergic dysfunction, in which energy protection was used, hypoergic damage, in which energy resuscitation was used, and hypoergic insufficiency, in which energy-correction technologies of personalized IT were used. Conclusions. 1. The conducted clinical study made it possible to develop additional technologies of personalized IT, which were used depending on the severity of energy-structural disorders in patients with ICS. The use of personalized IT technologies in patients with eubiotic and hypoergic ESST made it possible to reduce mortality, the number of complications and the time spent in intensive therapy units for patients with ICS. Traditional standard IT does not allow to prevent the development of the late form of multiple organ failure syndrome in patients with ICS.