{"title":"两种草本植物甲醇提取物的分离及对阿拉伯按蚊的杀幼虫活性评价。","authors":"Bouba Théophile, Saotoing Pierre, Ndjonka Dieudonné","doi":"10.35248/2329-891X.21.9.263","DOIUrl":null,"url":null,"abstract":"With the objective of controlling malaria by reducing the populations of Plasmodium spp, vectors, fractions obtained from crude extracts of dry plants of Cyperus rotundus and Leucas martinicensis were analyzed and their larvicidal activity on Anopheles arabiensis determined. Biological tests revealed that the hexane fraction of Cyperus rotundus as well as the ethyl acetate fractions of Leucas martinicensis and Cyperus rotundus are the most effective, with respective LC50 of 52.43ppm, 54.26ppm and 57.21ppm. The corresponding LH50 are 3h 09min 11sec, 3h 29min 45sec and 3h 51min 01sec. Phytochemical tests showed that the ethyl acetate fraction of Cyperus rotundus contains more terpenoids (42.005 ± 0.615 g lupeol eq / 100g DM), followed by the hexane fractions of Leucas martinicensis (38.845 ± 0.215 g Lupeol eq. / 100g DM), Cyperus rotundus (36.1 ± 0.66 g eq. lupeol / 100g DM).","PeriodicalId":74002,"journal":{"name":"Journal of tropical diseases & public health","volume":"9 1","pages":"1-7"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fractionation of methanolic extracts from two herbaceous plants and evaluation of their larvicidal activity on Anopheles arabiensis.\",\"authors\":\"Bouba Théophile, Saotoing Pierre, Ndjonka Dieudonné\",\"doi\":\"10.35248/2329-891X.21.9.263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"With the objective of controlling malaria by reducing the populations of Plasmodium spp, vectors, fractions obtained from crude extracts of dry plants of Cyperus rotundus and Leucas martinicensis were analyzed and their larvicidal activity on Anopheles arabiensis determined. Biological tests revealed that the hexane fraction of Cyperus rotundus as well as the ethyl acetate fractions of Leucas martinicensis and Cyperus rotundus are the most effective, with respective LC50 of 52.43ppm, 54.26ppm and 57.21ppm. The corresponding LH50 are 3h 09min 11sec, 3h 29min 45sec and 3h 51min 01sec. Phytochemical tests showed that the ethyl acetate fraction of Cyperus rotundus contains more terpenoids (42.005 ± 0.615 g lupeol eq / 100g DM), followed by the hexane fractions of Leucas martinicensis (38.845 ± 0.215 g Lupeol eq. / 100g DM), Cyperus rotundus (36.1 ± 0.66 g eq. lupeol / 100g DM).\",\"PeriodicalId\":74002,\"journal\":{\"name\":\"Journal of tropical diseases & public health\",\"volume\":\"9 1\",\"pages\":\"1-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of tropical diseases & public health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35248/2329-891X.21.9.263\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of tropical diseases & public health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2329-891X.21.9.263","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
以减少疟原虫种群为防治疟疾的目的，分析了圆形沙柏(Cyperus rotundus)和马提兰(Leucas martinicensis)干燥植物粗提物的载体、组分，并测定了它们对阿拉伯按蚊的杀幼虫活性。生物试验结果表明，香柏的己烷部位、马提尼松和香柏的乙酸乙酯部位的抑菌效果最好，LC50分别为52.43ppm、54.26ppm和57.21ppm。相应的LH50分别为3h 09min 11sec、3h 29min 45sec和3h 51min 01sec。植物化学试验结果表明，香附的乙酸乙酯部位含有较多的萜类化合物(42.005±0.615 g lupeol eq / 100g DM)，其次是马提子的己烷部位(38.845±0.215 g lupeol eq. / 100g DM)，香附的己烷部位(36.1±0.66 g eq. lupeol / 100g DM)。
Fractionation of methanolic extracts from two herbaceous plants and evaluation of their larvicidal activity on Anopheles arabiensis.
With the objective of controlling malaria by reducing the populations of Plasmodium spp, vectors, fractions obtained from crude extracts of dry plants of Cyperus rotundus and Leucas martinicensis were analyzed and their larvicidal activity on Anopheles arabiensis determined. Biological tests revealed that the hexane fraction of Cyperus rotundus as well as the ethyl acetate fractions of Leucas martinicensis and Cyperus rotundus are the most effective, with respective LC50 of 52.43ppm, 54.26ppm and 57.21ppm. The corresponding LH50 are 3h 09min 11sec, 3h 29min 45sec and 3h 51min 01sec. Phytochemical tests showed that the ethyl acetate fraction of Cyperus rotundus contains more terpenoids (42.005 ± 0.615 g lupeol eq / 100g DM), followed by the hexane fractions of Leucas martinicensis (38.845 ± 0.215 g Lupeol eq. / 100g DM), Cyperus rotundus (36.1 ± 0.66 g eq. lupeol / 100g DM).
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