非小细胞肺癌的预后基于血浆碱性成纤维细胞生长因子表达的临界值

Oncogen Pub Date : 2019-01-01 DOI:10.35702/onc.10017

L. Núñez-Naveira, C. Montero-Martínez, L. Mariñas-Pardo

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引用次数: 0

摘要

背景:血管生成受血管生成因子如血管内皮生长因子(VEGF)和碱性成纤维细胞生长因子(bFGF)的调控，这些因子在肺癌中可能不受调控。本研究旨在发现非小细胞肺癌(NSCLC)患者和健康志愿者(吸烟者和非吸烟者)呼出液(EBC)和血清中VEGF和bFGF蛋白的表达规律，以获得早期诊断价值，鉴别疾病的早期阶段。

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Non-Small Cell Lung Cancer Prognosis Based In A Cut-Off Value For Plasma Basic Fibroblast Growth Factor Expression

Background: Angiogenesis is regulated by angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) that may be deregulated in lung cancer. The aim of this study was to find out a pattern of VEGF and bFGF protein expression in exhaled breath condensate (EBC) and serum of non-small cell lung cancer (NSCLC) patients and healthy volunteers (smokers and nonsmokers) to obtain early diagnostic values to discriminate initial stages of disease.

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Oncogen

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