光学相干断层成像和拉曼光谱在癌症诊断中的应用前景

IF 0.3 Q4 SPECTROSCOPY

Biomedical Spectroscopy and Imaging Pub Date : 2015-01-01 DOI:10.3233/BSI-140097

K. Divakar Rao, N.K. Sahoo, C. Murali Krishna

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引用次数: 5

摘要

生物医学光学成像和光谱学正迅速成为非侵入性光学活检的有力竞争者。在生物医学成像中，光学相干层析成像(OCT)是一种成熟的非接触深度分辨率的微米级三维成像方式。OCT提供无标记的组织微观结构形态信息。拉曼光谱是获得分子特异性诊断信息的补充工具。本文简要介绍了OCT和拉曼光谱的基本原理，以及它们在癌症诊断中具有代表性的最新发展。

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Perspectives of optical coherence tomography imaging and Raman spectroscopy in cancer diagnosis

Biomedical optical imaging and optical spectroscopy are rapidly emerging as strong contenders for non-invasive optical biopsy. In biomedical imaging, Optical Coherence Tomography (OCT) is an established imaging modality for non- contact depth-resolved three-dimensional imaging with micrometer scale resolution. OCT provides label-free micro-structural morphological information of the tissue. Raman spectroscopy is a complementary tool for obtaining molecular-specific infor- mation for diagnosis. This article provides a brief overview of the underlying principles of OCT and Raman spectroscopy, their instrumentation with representative latest developments in cancer diagnosis.

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Biomedical Spectroscopy and Imaging SPECTROSCOPY-

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期刊介绍： Biomedical Spectroscopy and Imaging (BSI) is a multidisciplinary journal devoted to the timely publication of basic and applied research that uses spectroscopic and imaging techniques in different areas of life science including biology, biochemistry, biotechnology, bionanotechnology, environmental science, food science, pharmaceutical science, physiology and medicine. Scientists are encouraged to submit their work for publication in the form of original articles, brief communications, rapid communications, reviews and mini-reviews. Techniques covered include, but are not limited, to the following: • Vibrational Spectroscopy (Infrared, Raman, Teraherz) • Circular Dichroism Spectroscopy • Magnetic Resonance Spectroscopy (NMR, ESR) • UV-vis Spectroscopy • Mössbauer Spectroscopy • X-ray Spectroscopy (Absorption, Emission, Photoelectron, Fluorescence) • Neutron Spectroscopy • Mass Spectroscopy • Fluorescence Spectroscopy • X-ray and Neutron Scattering • Differential Scanning Calorimetry • Atomic Force Microscopy • Surface Plasmon Resonance • Magnetic Resonance Imaging • X-ray Imaging • Electron Imaging • Neutron Imaging • Raman Imaging • Infrared Imaging • Terahertz Imaging • Fluorescence Imaging • Near-infrared spectroscopy.