土耳其肾供者的人口学特征和供者-受者关系对术后结果的影响:单中心经验

O. Açıkgöz, Mert Altınel
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引用次数: 0

摘要

目的:肾移植(KTx)是终末期肾病(ESRD)患者最有效的治疗选择。活体供体肾移植是独一无二的,因为它涉及到接受大手术的健康个体。本回顾性研究旨在探讨供体-受体关系对土耳其供体接受腹腔镜供肾切除术(DNx)的术后结果的影响。材料与方法:本研究共纳入297例行左侧DNx的患者。将纳入研究的患者根据与受体关系的程度分为6个不同的组:69例以母亲为肾供体的DNx患者分为1组,29例以父亲为肾供体的DNx患者分为2组,70例以配偶为肾供体的DNx患者分为3组,68例以兄弟姐妹为肾供体的DNx患者分为4组,31例以子女为肾供体的DNx患者分为5组,30例以二度及更远的亲属为肾供体的DNx患者分为6组。回顾性分析并记录患者的年龄、性别、文化程度、手术时间(ST)、术后第1天视觉模拟评分(VAS)疼痛评分、住院时间(HS)、生活质量(QoL)等资料。结果:两组患者VAS评分、HS、QoL-MS均有显著差异。进行后置分析以找出哪些组有显著差异。结果显示,1组患者VAS评分明显低于2、3、6组。3、6组HS明显延长。2、6组患者qol - ms明显低于其他各组。结论:活体肾供者与受者的关系程度影响其术后早期的心理健康状况,并可能影响VAS评分和住院时间。可以说,母亲是受肾脏捐赠过程影响最小的捐赠者群体。关键词:肾;移植;活供体;捐助者与接受者的关系
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Demographic characteristics of Turkish kidney donors and the impact of donor-recipient relationship on postoperative outcomes: A single-center experience
Objective: Kidney transplantation (KTx) is the most effective treatment option for patients with end-stage renal disease (ESRD). Live donor kidney transplantation is unique as it involves healthy individuals who undergo a major surgery. This retrospective study seeks to investigate the effect of donor–recipient relationship on postoperative outcomes in Turkish donors undergoing laparoscopic donor nephrectomy (DNx). Material and Methods: The study was conducted with a total of 297 patients who underwent left DNx. The patients included in the study were divided into six different groups based on the degree of relationship with the recipients: Sixty-nine cases of DNx involved mothers as kidney donors classified into group-1, 29 cases involving fathers into group-2, 70 cases involving spouses into group-3, 68 cases involving siblings into group-4, 31 cases involving children into group-5, and 30 cases involving second-degree and more distant relatives into group-6. Patients’ data including age, sex, education level, duration of surgery (ST), Visual Analog Scale (VAS) pain score at postoperative day 1, length of hospital stay (HS), and Quality of Life (QoL) were retrospectively analyzed and recorded. Results: The groups had significant differences in terms of VAS scores, HS, and QoL-MS. Posthoc analysis was performed to find out which groups had significant differences. Results showed that group-1 had significantly lower VAS scores than group-2, group-3, and group-6. HS was significantly long in group-3 and group-6. QoL-MSwas significantly lower in group-2 and group-6 than the other groups. Conclusion: The degree of relationship of living kidney donors to recipients influences their psychological health in the early postoperative period and probably affects VAS scores and length of hospital stay. It can be argued that mothers are the group of donors least affected by the kidney donation process. Keywords: kidney; transplantation; live donor; donor-recipient relationship
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