基于患者年龄的结直肠癌的比较研究

N. Dhahir, A. Noaman
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引用次数: 2

摘要

摘要:背景:排便习惯改变、直肠出血和贫血是本研究中两组患者的共同特征,但在年轻患者中,由于没有怀疑和调查疾病,从出现症状到最终诊断之间延迟了6个月。年轻患者最常见的肿瘤部位是直肠,40岁以上的患者最常见的肿瘤部位是乙状结肠。病理结果显示,年轻患者的结直肠肿瘤分类为中分化至低分化腺癌,这表明年轻患者的病程更恶性。本研究向所有临床医生传达了一个信息,即年轻患者中结直肠癌的发病率正在上升,因此我们在处理出现腹痛、直肠出血和排便习惯改变的年轻患者时应提高警惕,及早诊断并进行治疗性手术。研究目的:研究结直肠癌临床发病年龄(40岁以下至40岁以上)、最常见部位、分布及手术干预方式。患者和方法:2012年1月至2013年3月,Al-Yarmouk医院收治了35例结直肠癌患者,其中年龄在40岁以下的患者10例(男5例,女5例),年龄在22-40岁之间,年龄在40岁以上的患者25例(男12例,女13例)。结果:40岁以下患者100%表现为贫血,50%表现为单直肠出血,40岁以上患者88%表现为虚弱和嗜睡。40岁以下患者占30%,40岁以上患者占36%,其余为择期病例。手术治疗涉及40岁以下患者的50%采用左、右半结肠切除术和前切除术,40岁以上患者的56%采用左半结肠切除术。在年轻患者中更常见的阶段是C和B,但在老年患者中则是A、B、C。建议:研究人员建议医生进行定期筛查,以早期诊断肿瘤,同时需要制定有关结直肠癌早期症状的教育计划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Comparative Study of Colorectal Cancer Based on Patient’s Age
Abstract: Background: The alteration of bowel habits, bleeding per-rectum and anemia were common features in both groups in this study, but in young patients there was a delay of 6 months between the presenting symptoms and the definitive diagnosis because the disease was not suspected and investigated in them. The most common site for the tumors in young patients was the rectum and in patients above the age of 40 years was the Sigmoid. The pathological finding showed that classification of the colorectal tumors in young patients appear moderately to poorly differentiated adenocarcinoma , this indicate a more malignant course of the disease in young patients. This study send a message to all clinicians that the incidence of colorectal cancer is increasing in young patients and therefore we should be alert when dealing with young patients presenting with abdominal pain, bleeding per-rectum and alteration of bowel habit to diagnose the disease at an early stage to undertake curative surgery . Aim of the study: To study the clinical coarse of colorectal cancer in age between (less than 40 to above 40), and the most frequent site and distribution, and the types of surgical intervention. Patients and methods: In the period between January 2012 to March 2013, 35 patients with colorectal cancer were treated at Al-Yarmouk Hospital,10 patients were below the age of 40 years ,( 5 Males and 5 Females ) with age ranging from 22-40 years , 25 patients were above the age of 40 years (12 males and13 females). Results:100% of patients less than 40 years presenting as anemia and 50% bleeding per rectum, while 88% of patients above 40 years with weakness and lethargy.30% of patients less 40years age, and 36% of patients above 40 years consider as an emergency cases, and others as elective cases. Surgical treatment involving 50% of patients less than 40 are right, left hemicolectomy and anterior resection, and in age of above 40 56% by left hemicolectomy. More common stages in young patents are  C and B  but in old  A ,B , C. Recommendations: Researchers recommend periodic screening by a doctor to diagnose the tumor early with the need to develop educational programs on early signs of colorectal cancer.
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