自体富血小板血浆——跟骨后滑囊炎的生物治疗选择及其相关性

Madhan Jeyaraman, Vishalkumar S Patel, Hardik J Dhamshania, Naveen Jeyaraman, Preethi Selvaraj
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引用次数: 0

摘要

背景:跟骨后滑囊炎是指跟腱前部和跟骨后部之间的滑囊炎症,与跟腱炎、足底筋膜炎、跟骨刺、纤维肌痛和类风湿关节炎有关。目的:本研究对一系列有症状的跟骨后滑囊炎患者及其相关性进行前瞻性回顾,以确定PRP注射是否(1)提供症状缓解,(2)改善VAS和AOFAS评分,(3)减轻手术需求。材料与方法:经病例筛选,128例患者接受自体富血小板血浆注射治疗,并给予相应的术前和术后护理。分别于第0天、第1周末、第1月和第6个月随访疼痛和活动范围。对患者的并发症进行随访,并对数据进行统计分析。结果:128例患者中,76例(59.37%)患者在第一次给药后症状得到改善,38例(29.68%)患者在第一次给药后间隔3周进行第二次自体PRP注射。接受自体PRP注射的患者中,89.05%的患者在注射1年后仍有良好的临床和功能结局,p值<0.001,差异有统计学意义。在研究参与者中未发现不良反应和严重并发症。结论:自体PRP注射治疗跟骨后滑囊炎疗效显著,可减轻患者的疼痛,提高患者的功能生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Autologous Platelet Rich Plasma-A Biological Therapeutic Option for Retrocalcaneal Bursitis and its Associations
Background: Retrocalcaneal bursitis is the inflammation of the bursa between the anterior aspect of the Achilles and posterior aspect of the calcaneum which is associated with achilles tendinitis, plantar fasciitis, calcaneal spurs, fibromyalgia and rheumatoid arthritis. Objectives: This study is conducted to review a series of patients prospectively with symptomatic retrocalcaneal bursitis and its associations to determine if PRP injections (1) provide symptomatic relief, (2) improved VAS and AOFAS scores and (3) alleviation of need of surgery. Materials and Methods: After screening of cases, 128 cases entered into the study and have been treated with an autologous platelet rich plasma injection with due pre and post procedural care. The cases are followed up on day 0, at the end of 1st week, 1st and 6th month for pain and range of movements. The patients are followed up for complications and the data were analyzed statistically. Results: Out of 128 cases, 76 patients (59.37%) improved with 1st dose and a further 38 patients (29.68%) with a 2nd dose of autologous PRP injection with an interval of 3 weeks from the first dose. A total of 89.05% of patients, who got treated with autologous PRP injection, had a good clinical and functional outcome even at the end of 1 year of injections and presented with statistically significant results with a p value <0.001. No adverse reactions and serious complications are noted in the study participants. Conclusion: The autologous PRP injection is considered superior in treatment of retrocalcaneal bursitis, which minimise the pain and improve the functional quality of life.
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