会阴部原发性恶性间皮瘤1例报告,表现为阴囊脓肿

Zhiwei Li, Qiqi Zhu, K. Xiao, Z. Xiao, P-J Yang
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摘要

男性,57岁,阴囊红斑疼痛1周,阴囊破裂脓液渗出1天。查体示左侧阴囊肿大,有一小块皮肤破裂,睾丸后下部靠近会阴处可见破裂处黄白色分泌物,局部皮肤温度稍高,压痛,波动感。最初的生殖系统超声和盆腔CT提示炎症感染,两次手术后组织学证实。患者病情长期无好转,复查盆腔CT提示腹股沟多发肿大淋巴结。细针穿刺细胞学提示转移性癌。会阴阴囊区组织病理及免疫组化示恶性间皮瘤,全身PET-CT提示肺转移及浸润周围组织,如生殖系统脏器。患者接受了化疗和免疫治疗,但病情进展迅速,最终死于呼吸衰竭。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Report of a Rare Case of Primary Malignant Mesothelioma of the Perineum Presenting as a Scrotal Abscess
A 57-year-old man presented with erythema and pain in the scrotum for 1 week, with pus exuding from the ruptured scrotum for 1 day. Physical examination showed an enlarged left scrotum, with a small area of ruptured skin, and yellowish-white discharge from the rupture was visible in the lower posterior part of the testes near the perineum, with slightly high local skin temperature, tenderness, and fluctuating sensation. The initial reproductive system ultrasound and pelvic CT were suggestive of inflammatory infection, which was confirmed by histology following two surgeries. The patient's condition did not show improvement for a long period of time, and repeat pelvic CT suggested multiple enlarged inguinal lymph nodes. Fine needle aspiration cytology suggested metastatic cancer. Histopathological examination and immunohistochemistry of the perineal scrotal area showed malignant mesothelioma, and whole-body PET-CT suggested pulmonary metastases and invasion into the surrounding tissues, such as the organs of the reproductive system. The patient received chemotherapy and immunotherapy, but the disease progressed rapidly, and he ultimately died of respiratory failure.
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