Stefan Günther, A. Reimer, H. Vogl, Stephan Spenke, Hanns-Christian Dinges, A. Schubert, Leopold Hj Eberhart, G. Geldner
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Determination of Meropenem, Ceftazidime and Piperacillin Levels in Serum and Meropenem in Cerebrospinal Fluid by Liquid Chromatography for Routine Quantification
((4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-Abstract Objective: Therapeutic drug monitoring (TDM) of β-lactam antibiotics is a commonly used to prevent treatment failures in critically ill patients. A quick and simple high-performance liquid chromatography (HPLC) assay for the determination of meropenem, ceftazidime and piperacillin in human serum and meopenem in