立体定向放射手术治疗脑转移的成本-效果:系统综述

Saude Tecnologia Pub Date : 2016-12-28 DOI:10.25758/SET.1461
Leandro Luís
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引用次数: 1

摘要

摘要:导读-脑转移是肿瘤疾病的一个问题,它严重限制了患者的生存和生活质量。立体定向放射外科揭示了一种非侵入性脑转移瘤切除。目的:验证立体定向放射手术治疗脑转移癌患者是否比其他治疗方法更具成本效益。方法:我们对2005年至2015年间使用EBSCO主机和PubMed的文献进行了系统综述。搜索词是“放射外科”、“脑”、“转移”、“经济学”和“成本效益分析”。调查显示了57篇可能符合审查条件的文章,这些文章将根据确定的选择标准进行评估。三篇文章被纳入综述。结果和讨论-回顾显示立体定向放射手术在两种替代研究(脑全辐射和传统手术切除转移瘤)中占主导地位。这种优势与立体定向放射手术的低成本和相同或更好的效果(有效性或效用)有关。立体定向放射手术的成本似乎是与其他治疗方法相比的关键区别,在这三项研究中,立体定向放射手术的成本比其他治疗方法低。结论:使用立体定向放射手术的相关费用和效果表明,这将是更合理治疗脑转移患者的最佳选择。然而,由于本综述中评估研究的稀缺性,研究结果是有限的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Custo-efetividade da radiocirurgia estereotáxica no tratamento de metástases cerebrais: revisão sistemática
ABSTRACT: Introduction – Brain metastases are a problem due to the oncologic disease, which significantly limit patient survival and their quality of life. The stereotactic radiosurgery discloses a non-invasive removal of brain metastases. Objectives – Verify if stereotactic radiosurgery is more cost-effective than alternative treatments for brain metastases in cancer patients. Methods – We conducted a systematic review of literature using EBSCO host and PubMed between 2005 and 2015. The search terms were ‘radiosurgery’, ‘brain’, ‘metastasis’, ‘economics’, and ‘cost-benefit analysis’. The survey revealed 57 potentially eligible articles for the review, which were subject to an evaluation in accordance with the defined selection criteria. Three articles were included in the review. Results and Discussion – The review showed stereotactic radiosurgery dominance in relation to the two alternatives studied (total radiation of the brain and traditional surgery for resection of metastases). This superiority is associated with lower costs and equal or better effects (effectiveness or utility) of stereotactic radiosurgery. The cost of stereotacticradiosurgery seems to be the key differentiator relative to alternative treatments, lower than them in the three studies. Conclusion – The associated costs and effects of using stereotactic radiosurgery suggest that this will be the best option for a more rational treatment of patients with brain metastases. However, the findings are limited because of the scarcity of evaluated studies in the review.
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