Ajinkya Raut, P. Renner, Rick Wang, S. Kazadi, Siddhi Mehta, Yan Chen, Hong Liang
{"title":"高分子刷在生物应用中的作用","authors":"Ajinkya Raut, P. Renner, Rick Wang, S. Kazadi, Siddhi Mehta, Yan Chen, Hong Liang","doi":"10.25082/AB.2021.01.001","DOIUrl":null,"url":null,"abstract":"Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling a brush. They have shown variety of uses in biological applications. Because of the nature of crafted polymers, the functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters such as grafting densities, chemical configurations, shapes and thickness. In this review, a particular emphasis has been provided for studies related to biological applications of polymer brushes based on their ultra-low friction, hydrophilic elongated surfaces, and binding properties. It provides useful information for researches and labs working on finding better solutions for drug delivery, arthritis, artificial joints, antibiofouling coatings and protein immobilization and purification.","PeriodicalId":69883,"journal":{"name":"生物芯片进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Roles of polymer brushes in biological applications\",\"authors\":\"Ajinkya Raut, P. Renner, Rick Wang, S. Kazadi, Siddhi Mehta, Yan Chen, Hong Liang\",\"doi\":\"10.25082/AB.2021.01.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling a brush. They have shown variety of uses in biological applications. Because of the nature of crafted polymers, the functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters such as grafting densities, chemical configurations, shapes and thickness. In this review, a particular emphasis has been provided for studies related to biological applications of polymer brushes based on their ultra-low friction, hydrophilic elongated surfaces, and binding properties. It provides useful information for researches and labs working on finding better solutions for drug delivery, arthritis, artificial joints, antibiofouling coatings and protein immobilization and purification.\",\"PeriodicalId\":69883,\"journal\":{\"name\":\"生物芯片进展(英文)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"生物芯片进展(英文)\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.25082/AB.2021.01.001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"生物芯片进展(英文)","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.25082/AB.2021.01.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Roles of polymer brushes in biological applications
Polymer brushes are macromolecular structures with polymer chains tethered to a surface resembling a brush. They have shown variety of uses in biological applications. Because of the nature of crafted polymers, the functionalized surfaces exhibit unique functions such as low friction, altered adhesion, protein binding and selective adsorption. Functionalization can be controlled by changing parameters such as grafting densities, chemical configurations, shapes and thickness. In this review, a particular emphasis has been provided for studies related to biological applications of polymer brushes based on their ultra-low friction, hydrophilic elongated surfaces, and binding properties. It provides useful information for researches and labs working on finding better solutions for drug delivery, arthritis, artificial joints, antibiofouling coatings and protein immobilization and purification.