α -1-抗胰蛋白酶预测高血糖状态下严重的covid-19、胃癌和肾癌

IF 0.3 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
I. Komarevtseva, S. Smirnov, A. Ihnatova, I. Rudenko, K. Balabanova, I. A. Vyshnitska, V. Komarevtsev
{"title":"α -1-抗胰蛋白酶预测高血糖状态下严重的covid-19、胃癌和肾癌","authors":"I. Komarevtseva, S. Smirnov, A. Ihnatova, I. Rudenko, K. Balabanova, I. A. Vyshnitska, V. Komarevtsev","doi":"10.26724/2079-8334-2023-1-83-100-105","DOIUrl":null,"url":null,"abstract":"Hyperglycemia with or without blood glucose in diabetes range is an emerging finding not uncommonly encountered in patients with COVID-19. This work is to investigate the association between serum alpha-1-antitrypsin, hyperglycemia, and clinical outcomes in COVID-19, and community-acquired pneumonia, gastric cancer and renal cell carcinoma. Alpha-1-antitrypsin levels in serum was determined by the immunoturbidimetric method. We have set the level of alpha-1-antitrypsin in patients with community-acquired pneumonia and COVID-19 with or without hyperglycemia. Levels of alpha-1-antitrypsin in COVID-19 patients with hyperglycemia who survived > those who did not survive. Concentration of alpha-1-antitrypsin levels in COVID-19 men-patients with hyperglycemia who survived was significantly higher than compared with COVID-19 women-patients with hyperglycemia who survived. The obtained data convincingly demonstrate the value of testing the level of alpha-1-antitrypsin in the blood as one of the important indicators of the effectiveness of cancer diagnosis and prognosis.","PeriodicalId":23771,"journal":{"name":"World of Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"ALFA-1-ANTITRYPSIN PREDICTS SEVERE COVID-19, GASTRIC AND RENAL CANCER IN CONDITIONS OF HYPERGLYCEMIA\",\"authors\":\"I. Komarevtseva, S. Smirnov, A. Ihnatova, I. Rudenko, K. Balabanova, I. A. Vyshnitska, V. Komarevtsev\",\"doi\":\"10.26724/2079-8334-2023-1-83-100-105\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hyperglycemia with or without blood glucose in diabetes range is an emerging finding not uncommonly encountered in patients with COVID-19. This work is to investigate the association between serum alpha-1-antitrypsin, hyperglycemia, and clinical outcomes in COVID-19, and community-acquired pneumonia, gastric cancer and renal cell carcinoma. Alpha-1-antitrypsin levels in serum was determined by the immunoturbidimetric method. We have set the level of alpha-1-antitrypsin in patients with community-acquired pneumonia and COVID-19 with or without hyperglycemia. Levels of alpha-1-antitrypsin in COVID-19 patients with hyperglycemia who survived > those who did not survive. Concentration of alpha-1-antitrypsin levels in COVID-19 men-patients with hyperglycemia who survived was significantly higher than compared with COVID-19 women-patients with hyperglycemia who survived. The obtained data convincingly demonstrate the value of testing the level of alpha-1-antitrypsin in the blood as one of the important indicators of the effectiveness of cancer diagnosis and prognosis.\",\"PeriodicalId\":23771,\"journal\":{\"name\":\"World of Medicine and Biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World of Medicine and Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26724/2079-8334-2023-1-83-100-105\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World of Medicine and Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26724/2079-8334-2023-1-83-100-105","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 1

摘要

糖尿病范围内伴有或不伴有血糖的高血糖是一种新发现,在COVID-19患者中并不罕见。本研究旨在探讨COVID-19患者血清α -1抗胰蛋白酶、高血糖和临床结局与社区获得性肺炎、胃癌和肾细胞癌的关系。免疫比浊法测定血清α -1-抗胰蛋白酶水平。我们对伴有或不伴有高血糖的社区获得性肺炎和COVID-19患者的α -1抗胰蛋白酶水平进行了设定。存活的COVID-19高血糖患者的α -1-抗胰蛋白酶水平与未存活的患者相比。存活的COVID-19男性高血糖患者的α -1抗胰蛋白酶浓度显著高于存活的COVID-19女性高血糖患者。所获得的数据令人信服地证明了检测血液中α -1-抗胰蛋白酶水平作为癌症诊断和预后有效性的重要指标之一的价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ALFA-1-ANTITRYPSIN PREDICTS SEVERE COVID-19, GASTRIC AND RENAL CANCER IN CONDITIONS OF HYPERGLYCEMIA
Hyperglycemia with or without blood glucose in diabetes range is an emerging finding not uncommonly encountered in patients with COVID-19. This work is to investigate the association between serum alpha-1-antitrypsin, hyperglycemia, and clinical outcomes in COVID-19, and community-acquired pneumonia, gastric cancer and renal cell carcinoma. Alpha-1-antitrypsin levels in serum was determined by the immunoturbidimetric method. We have set the level of alpha-1-antitrypsin in patients with community-acquired pneumonia and COVID-19 with or without hyperglycemia. Levels of alpha-1-antitrypsin in COVID-19 patients with hyperglycemia who survived > those who did not survive. Concentration of alpha-1-antitrypsin levels in COVID-19 men-patients with hyperglycemia who survived was significantly higher than compared with COVID-19 women-patients with hyperglycemia who survived. The obtained data convincingly demonstrate the value of testing the level of alpha-1-antitrypsin in the blood as one of the important indicators of the effectiveness of cancer diagnosis and prognosis.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
World of Medicine and Biology
World of Medicine and Biology MEDICINE, RESEARCH & EXPERIMENTAL-
自引率
0.00%
发文量
56
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信