Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain, Y. Chen
{"title":"黄芩苷的提取、抗癌作用、生物利用度及纳米技术研究","authors":"Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain, Y. Chen","doi":"10.23937/2572-3278.1510011","DOIUrl":null,"url":null,"abstract":"The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":"2 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":"{\"title\":\"The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin\",\"authors\":\"Ondrea A. Moore, Ying Gao, Allen Y. Chen, Ross Brittain, Y. Chen\",\"doi\":\"10.23937/2572-3278.1510011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.\",\"PeriodicalId\":91758,\"journal\":{\"name\":\"Journal of nutritional medicine and diet care\",\"volume\":\"2 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-03-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"18\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of nutritional medicine and diet care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23937/2572-3278.1510011\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of nutritional medicine and diet care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2572-3278.1510011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Extraction, Anticancer Effect, Bioavailability, and Nanotechnology of Baicalin
The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we present the main extraction methods, anticancer activity and bioavailability of baicalin. Besides, the utilization of nanotechnology to improve the bioavailability of baicalin is also mentioned.