甲状腺髓样癌淋巴结转移的手术治疗

IF 1.2

International Journal of Endocrine Oncology Pub Date : 2015-08-28 DOI:10.2217/IJE.15.15

L. Jin, J. Moley

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引用次数: 0

摘要

甲状腺髓样癌(MTC)是一种甲状腺C细胞的神经内分泌恶性肿瘤，通常可以扩散到颈部和纵隔淋巴结。MTC细胞不浓缩放射性碘，对激素操作不敏感，因此手术是治愈性治疗、减少肿瘤负担或有效缓解的唯一有效选择。对于遗传性MTC的预防性手术患者，如果降钙素水平高于40 pg/ml，则应考虑中央淋巴结清扫。对于所有可触及的原发性肿瘤和复发性疾病的患者，应系统地切除高危或受累的淋巴结室，并应避免“采摘”方法。

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Surgery for lymph node metastases of medullary thyroid carcinoma

Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy of the thyroid C cells, and can commonly spread to cervical and mediastinal lymph nodes. MTC cells do not concentrate radioactive iodine and are not sensitive to hormonal manipulation, and therefore surgery is the only effective option for curative therapy, reduction in tumor burden or effective palliation. In patients undergoing preventative operations for hereditary MTC, central lymph node dissection should be considered if the calcitonin level is above 40 pg/ml. Systematic removal of at-risk or involved lymph node compartments should be performed in all patients with palpable primary tumors and recurrent disease, and a ‘berry-picking’ approach should be avoided.

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来源期刊

International Journal of Endocrine Oncology ONCOLOGY-

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： International Journal of Endocrine Oncology is a quarterly, peer-reviewed journal that helps the clinician to keep up to date with best practice in this fast-moving field. The journal highlights significant advances in basic and translational research, and places them in context for future therapy. The journal presents the latest research findings in diagnosis and management of endocrine cancer, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. The journal welcomes the unsolicited submission of article proposals and original research manuscripts.