生育能力:乳腺癌患者乳房切除术后疼痛综合征的控制因素

M. Hashemian, Mohammad Reza Aflatoonian, Behnaz Aflatoonian, M. Akbari, A. Akbari
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摘要

背景:通常情况下,手术是治疗乳腺癌的首选,但其副作用是慢性疼痛。乳房切除术后疼痛综合征(PMPS)是乳腺癌幸存者中最常见的副作用之一,是一种持续超过三个月的慢性神经性疼痛。与乳房手术后慢性疼痛相关的确切机制和危险因素尚未确定。目的:本研究旨在确定生育能力对乳腺癌患者乳房手术后PMPS的影响。方法:采用病例对照研究方法,对111例妇女进行研究。其中,56名女性被诊断为PMPS阳性并被放置在病例组,55名无疼痛的患者被选择为对照组。通过问卷调查和病历资料收集患者的人口学和临床资料。在SPSS 22软件中采用描述性统计和推理统计、卡方、Mann-whitney U、回归logistic (Backward)等方法对数据进行分析。结果:根据获得的结果,研究人群的平均年龄为49.77 10.94,平均体重为69.5 11.45 kg,平均身高为160 8.14 cm,平均BMI为27.4 5.4。总而言之,结果表明,与没有生育能力的女性相比,有生育能力的女性更有可能不会因经前症候群而死亡,而且心理障碍与经前症候群之间没有关联
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Fertility: A Control Factor for Post Mastectomy Pain Syndrome in Breast Cancer Patients
Background: Normally, surgery is the first choice of treatment for breast cancer which brings about side eects as chronic pain. Post mastectomy pain syndrome (PMPS) is one of the most prevalent side eects in breast cancer survivors as a chronic neuropathic pain lasting more than three months. The precise mechanisms and risk factors connected to chronic pain after breast surgery are not identified. Objectives: This study is aimed at identifying the eects of fertility on PMPS after breast surgery in breast cancer patients. Methods: In this case-control study, a total number of 111 women were studied. Of these, 56 women were diagnosed with positive PMPS and place in the case group, and 55 patients without pain were selected as the control group. The patients' demographic and clinical information were collected by means of a questionaire and their medical files. Descriptive statistics and inferential statistics, chi-square, Mann-whitney U, Regression Logisitic (Backward), were used to analyze the data in SPSS 22 software. Results: According to the acquired results, the mean age of the study population was 49.77 10.94, the mean weight was 69.5 11.45 kg, the mean height was 160 8.14 centimeter and mean BMI was 27.4 5.4. All in all, the results showed that fertile women were more likely not to suer from PMPS compared to nulipar women, and there was not a correlation between psychological disorders
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