Alrx, er A. Bukhvostov, A. Dvornikov, K. Ermakov, D. Kuznetsov
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Retinoblastoma Case: Shall we Get A Paramagnetic Trend in Chemotherapy?
We have performed our study on a NEN-treated RB cell culture derived from a real clinical autopsy material. 3.5- year-old male donor has died of a massive complex abdominal trauma being previously RB-diagnosed with NMR and ultrasound tests, tumor located behind the eye globe equator line. This is a first report ever on magnetic isotope effects of metal ions to cause the clear anti-cancer consequences in retinoblastoma cells by depriving them of the DNA repair capabilities. Both molecular mechanism of phenomenon and its possible meaning for retinoblastoma chemotherapy are presented here.
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