干细胞注射对犬二头肌肌腱炎和腱鞘炎再生治疗的超声监测

IF 0.4 4区 农林科学 Q4 VETERINARY SCIENCES
Aleksiewicz Roman, Lutnicki Krzysztof, Marcinek Tomasz
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引用次数: 0

摘要

损伤和超载的二头肌肌腱在狗是一个常见的原因二头肌腱炎和腱鞘炎(BBT)。本研究的目的是评估超声监测在BBT再生治疗中的优势以及狗主人对治疗的评估。研究中使用了32只雌雄狗。采用富血小板血浆(ADMSC + PRP)脂肪源性间充质干细胞治疗,每次0.5 ml (15.0 × 106个细胞/ml),两次给药。将ADMSC + PRP注入肱二头肌肌腱鞘,将0.5 ml注入肱关节腔。在研究期间,根据犬简要疼痛发明人-佩恩图表(CBPI)进行疼痛评估,并进行超声扫描。超声图像上的一些变化是永久性的,恢复是渐进的和不完整的。研究表明,超声波扫描结果与CBPI问卷的所有者之间存在相关性,这与再生治疗的效果有关。研究表明,ADMSC + PRP在4个月后对肱二头肌肌腱鞘和肱二头肌肌腱有再生作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ultrasound monitoring of the regenerative treatment of Biceps Tendonitis and Tenosynovitis in dogs by stem cells injections
Injuries and the overloading of the bicipital muscle tendon in dogs are a common cause of Bicipital Tendinitis and Tenosynovitis (BBT). The aim of the study was to evaluate the advantage of ultrasound monitoring during regenerative treatment of BBT together with treatment assessment by dog owners. 32 dogs of both sexes were used in the study. The dogs were treated with adipose-derived mesenchymal stem cells with platelet-rich plasma (ADMSC + PRP) administered twice in a dose of 0.5 ml (15.0 × 106 cells/ml). The ADMSC + PRP was injected into the tendon sheath of the biceps and 0.5 ml was injected into the brachial joint cavity. During the research, pain evaluation was performed according to the Canine Brief Pain Inventor – Penn CHART (CBPI), ultrasound scans were also performed. Some of the changes in ultrasound images are permanent and the recovery is gradual and incomplete. The research showed a correlation between the results of the ultrasound scans and the owners of the CBPI questionnaire, this was correlated with the effects of regenerative therapy. Studies have shown the regenerative effect of ADMSC + PRP on the tendon sheath and biceps tendon of the brachii after 4 months.
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
73
审稿时长
4-8 weeks
期刊介绍: "Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year. All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.
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