以烟酸及其衍生物为基础的药物在极端条件下的施用

Q4 Biochemistry, Genetics and Molecular Biology

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine Pub Date : 2022-01-01 DOI:10.21687/0233-528x-2022-56-4-35-43

V. Yasnetsov, D. E. Kaurova

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引用次数: 0

摘要

文献综述包括俄罗斯药物烟酰γ -氨基丁酸(picamilon)，羟嗪烟酰谷氨酸钙(ampasse)和含有烟酸及其衍生物的联合药物细胞黄素在极端条件下的效力的实验和临床证据。分析表明，这些药物和烟酸衍生物对不同原因的急慢性缺氧、低体温和高热、运动不足等有明显的保护作用。为了提高暴露于极端因素后医疗保健的效力和安全性，应进一步寻找其他烟酸衍生物。

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ADMINISTRATION IN EXTREME CONDITIONS OF MEDICAMENTS BASED ON NICOTINIC ACID AND ITS DERIVATIVES

The literary review encompasses the experimental and clinical evidence of the potency of Russian medicaments nicotinoyl gamma-aminobutyric acid (picamilon), hydroxyzine nicotinoyl glutamate calcium (ampasse), and combineddrug cytoflavin containing nicotinic acid and its derivatives in extreme conditions. Analysis shows that these medicaments and nicotinic acid derivatives protect tangibly from acute and chronic hypoxia of varying genesis, hypo- and hyperthermia, hypokinesia etc. To increase potency and safety of medical care after exposure to extreme factors the search for other nicotinic acid derivatives should be furthered.

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来源期刊

Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

0.60

自引率

0.00%

发文量