全基因组关联研究(GWAS)与功能验证:后GWAS时代的挑战

IF 0.8 Q4 ENDOCRINOLOGY & METABOLISM

Revista de Osteoporosis y Metabolismo Mineral Pub Date : 2023-01-01 DOI:10.20960/revosteoporosmetabminer.00008

S. Balcells, Núria Martínez-Gil, Juan David Patiño-Salazar, R. Rabionet, D. Grinberg

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Genome-wide association studies (GWAS) vs functional validation: the challenge of the post-GWAS era

Over the past few years, efforts have been made to determine the variants and genes that may be important to determine bone mineral density (BMD) that, at the same time, are involved in several bone diseases. To achieve this, the approach that has been the most successful of all has been genome-wide association studies (GWAS). In particular, in research on bone biology over 50 different large

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来源期刊

Revista de Osteoporosis y Metabolismo Mineral ENDOCRINOLOGY & METABOLISM-

CiteScore

0.80

自引率

16.70%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of Osteoporosis and Mineral Metabolism (Rev Osteoporos Metab Miner; www.revistadeosteoporosisymetabolismomineral.es) is the official organ of scientific expression of the Spanish Society for Bone Research and Mineral Metabolism (SEIOMM), who owns all rights over it. Its periodicity is quarterly (4 numbers a year, spring, summer, autumn and winter), with a variable number of extraordinary monographs. The third issue of the year, autumn, is intended for the publication of the communications of the annual Congress of the SEIOMM. The Journal of Osteoporosis and Mineral Metabolism (hereinafter ROMM) publishes works in Spanish, which will be translated into English, and is offered free of charge through its website.