术后病人呼吸并发症的风险因素

Д. П. Котова, В. С. Шеменкова
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引用次数: 0

摘要

呼吸系统疾病(包括急性和慢性疾病的恶化)仍然是各种规模的手术干预后最常见的非手术并发症,增加了患者的住院时间,增加了经济成本和死亡率。研究表明,腹部手术后出现的呼吸并发症使30天内死亡的风险增加了10倍。最常见的并发症包括:再插管、急性呼吸衰竭、肺水肿、肺不张和肺炎。呼吸道并发症的发生是由于呼吸系统和呼吸肌肉的病理。事实证明,在75%的病例中,使用抑制神经肌肉传导的药物会引起肺不张、呼吸肌功能障碍和呼吸量减少。呼吸系统并发症最常由缺氧或高碳酸血症引起。缺氧的特征是氧气分压的降低,通过额外的氧合可以很好地纠正。在手术后的第一个小时内,50 - 55%的病例发生低氧血症,饱和度下降高达80%。呼吸功能完全恢复正常通常发生在拔管后4-6小时。相反,高碳酸血症的特点是氧分压增加,出现高钾血症和呼吸性酸中毒现象。电解质和缓冲扰动的校正是必要的。对于临床医生来说,重要的是要记住需要识别可能的呼吸系统并发症的危险因素(可修改的和未修改的)以及纠正它们的方法。在计划手术前由治疗师对患者进行检查,包括在多学科医院的治疗部门进行可能的术前准备,有助于减少术后并发症的发生。在这篇文章中,作者描述了评估,预防和诊断围手术期呼吸并发症患者的共病病理的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Факторы риска респираторных осложнений у пациентов в периоперационном периоде
Diseases of the respiratory system (both acute and exacerbations of chronic ones) remain the most frequent non-surgical complications after surgical interventions of various sizes, increasing the duration of the patient»s hospital stay, increasing economic costs and the percentage of deaths. It was shown that respiratory complications developed after abdominal operations increased the risk of 30-day mortality by 10 times. The most common complications include: reintubation, acute respiratory failure, pulmonary edema, atelectasis and pneumonia. The development of respiratory complications is due to the pathology of the respiratory system and respiratory muscles. It is proved that the use of drugs that inhibit neuromuscular conduction in 75 % of cases provokes the development of atelectasis, respiratory muscle dysfunction and reduces respiratory volumes. Respiratory complications are most often caused by hypoxia or hypercapnia. Hypoxia is characterized by a decrease in the partial pressure of oxygen and is well corrected by additional oxygenation. In the first hours after surgery hypoxemia occurs in 50—55 % of cases with a decrease in saturation up to 80 %. Complete normalization of respiratory dysfunction usually occurs 4—6 hours after extubation. Hypercapnia, on the contrary, is characterized by an increase in the partial pressure of oxygen, the phenomena of hyperkalemia and respiratory acidosis. Correction of electrolyte and buffer disturbances is necessary. It is important for the Clinician to remember the need to identify possible risk factors for respiratory complications (modifiable and unmodified) and ways to correct them. Examination of the patient by a therapist before the planned operation, including possible preoperative preparation in the therapeutic departments of a multidisciplinary hospital helps to reduce the frequency of postoperative complications. In this article the authors describe recommendations for evaluation, prevention and diagnosis of respiratory complications in the perioperative period in patients with comorbid pathology.
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