嗜酸性粒细胞性食管炎的临床表现、诊断和治疗现状

Q3 Medicine

Voprosy Detskoi Dietologii Pub Date : 2023-01-01 DOI:10.20953/1727-5784-2023-1-52-65

A. Paraskevova, A. Trukhmanov, T. Lapina, S. S. Pirogov, A. Tertychny, O. Storonova, A. A. Makushina, V. Ivashkin

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引用次数: 0

摘要

嗜酸性粒细胞性食管炎(EoE)是一种免疫介导的疾病，其特征是吞咽困难和食管上皮嗜酸性粒细胞浸润，每高倍视场至少有15个细胞(×400)。目前，在世界范围内，EoE的发病率呈上升趋势。EoE患者包括成人和儿童。EoE的诊断需要形态学确认。EoE的诱因可以是空气过敏原和食物过敏原。EoE常伴有其他特应性疾病。EoE的治疗是基于质子泵抑制剂(PPIs)，局部糖皮质激素(GCs)和元素或消除饮食。本文对文献进行了详细的分析，并提出了EoE患者的治疗算法。关键词:特应性疾病，吞咽困难，嗜酸性粒细胞浸润，嗜酸性粒细胞性食管炎

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Eosinophilic esophagitis: clinical presentation, current aspects of diagnosis and treatment

Eosinophilic esophagitis (EoE) is an immune-mediated disease characterized by complaints of dysphagia and eosinophilic infiltration of the esophageal epithelium with at least 15 cells per high power field (×400). Currently, there has been an increase in the incidence of EoE worldwide. Patients with EoE include both adults and children. The diagnosis of EoE requires morphological confirmation. Triggers for EoE can be aeroallergens and food allergens. EoE is often accompanied by other atopic diseases. The treatment of EoE is based on proton pump inhibitors (PPIs), topical glucocorticosteroids (GCs), and elemental or elimination diets. This review presents a detailed analysis of literature and proposes the therapeutic algorithm for patients with EoE. Key words: atopic diseases, dysphagia, eosinophilic infiltration, eosinophilic esophagitis

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来源期刊

Voprosy Detskoi Dietologii Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.