评价母子功能的软件硬件综合体

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Иван Владиславович Толмачёв, Константин Станиславович Бразовский, Анастасия Сергеевна Цверова, В. С. Рипенко
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引用次数: 0

摘要

摘要在当今社会,母亲和胎儿的健康非常重要。及时诊断围产期病理,可以预防分娩损伤、产前死产和新生儿围产期死亡。目前,世界上还没有一种综合体能够在不危及胎儿健康的情况下监测胎儿。因此,本研究的主要目的是开发通过分析腹部电极记录的信号来评估母亲和胎儿功能状态的硬件和软件系统。目的:1)制定对无创监护系统及母婴功能状态评估的要求。2)开发母胎监测系统和功能状态评估的算法和软件。3)测定正常妊娠和胎盘功能不全处于代偿期和亚代偿期的32-33周胎儿功能状态。该系统的概念是基于胎儿心率的识别和分析。从腹部电极接收到的混合信号中提取胎儿心率。这种技术对身体来说是被动的,所以没有研究时间限制。胎儿和母亲心电图同时登记装置是高灵敏度生物放大器,具有低水平的固有噪声,高输入电阻,抑制80 DB以上的相位噪声。信号的数字处理由配准模块的单片机和个人计算机共同完成。预处理是在微控制器中通过增加采样率、数字滤波、抽取从模数转换器接收信号来完成的。借助已开发的复杂系统进行了两阶段的研究。第一阶段研究胎儿心脏间期图(即胎儿心跳周期和这些间隔时间的分布模式)。第二阶段是为了寻找在妊娠晚期伴有高雄激素血症的孕妇胎盘功能不全的胎儿功能状态评估的附加标准。因此,定义了妊娠32-35周心率结构参数可以评估功能障碍和胎儿缺氧发展的风险,敏感性Se = 80%,特异性Sp = 73%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ПРОГРАММНО-АППАРАТНЫЙ КОМПЛЕКС ДЛЯ ОЦЕНКИ ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ МАТЕРИ И ПЛОДА
Text abstract Mother’s and fetus’s health are very important in present time. With timely diagnosis perinatal pathology, birth injuries, antenatal stillbirths and newborn perinatal death can be prevented. At the moment in the world there are no complexes which enable monitoring of the fetus without any risk to his health. So the main aim of this work is development of hardware and software system to assess the functional status of the mother and fetus by the analysis of the signals recorded from the abdominal electrodes. Objectives: 1) to formulate the requirements to noninvasive monitoring system and functional state assessment of mother and fetus. 2) to develop algorithms and software for monitoring system and functional state assessment of mother and fetus. 3) to determine fetus functional state at 32–33 week in women with uncomplicated pregnancies and in women with placental insufficiency in the compensation stage and subcompensation. The system concept is based on fetal heart rate recognition and analysis. Fetal heart rate has been extracted from the mixed signals received from abdominal electrodes. This technique is passive for a body so there is no research time limit. Device for simultaneous registration of fetal and maternal electrocardiogram is high sensitive bioamplifier with low level of intrinsic noises, high input resistance and suppression of inphase noises more than 80 DB. Digital processing of a signal is carried out by microcontroller of the registration module and personal computer. Preprocessing is carried out in microcontroller by receiving signals from the analog-to-digital converter on the increased sampling rate, digital filtering, decimation. With the help of the developed complex two-stage study was conducted. At first stage the fetal cardiointervalogram (i.e. fetus heartbeat period and the distribution pattern of these intervals in time) was studied. Second stage was carried out to search additional criteria of fetal functional state assessment with placental insufficiency in the pregnant with hyperandrogenism in the third trimester. As result, it was defined, that parameters of heart rate structure at 32–35 weeks of gestation allows to assess the risk of functional disorders and development of fetus hypoxia with sensitivity Se = 80% and specificity Sp = 73%.
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来源期刊
Byulleten Sibirskoy Meditsiny
Byulleten Sibirskoy Meditsiny MEDICINE, GENERAL & INTERNAL-
CiteScore
0.70
自引率
50.00%
发文量
102
审稿时长
8 weeks
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