血管肌张力调节钠钾氯运输

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Byulleten Sibirskoy Meditsiny Pub Date : 2014-01-01 DOI:10.20538/1682-0363-2014-6-165-173

Сергей Николаевич Орлов, С. В. Кольцова, Яна Джоновна Анфиногенова, Леонид Владимирович Капилевич, Светлана Валерьевна Гусакова, Л. В. Смаглий, М. Б. Баскаков, Михаил Андреевич Медведев

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引用次数: 1

摘要

本文讨论了钠、钾、氯离子电中性同调载体Na +、K +、2Cl -共转运的功能及其调控的分子机制和生理意义。我们分析了Na +，K +，2Cl -共转运体(NKCC1)泛在异构体参与血管平滑肌收缩调控的新数据，以及该载体在调节细胞体积和细胞内氯离子浓度中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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НАТРИЙ-КАЛИЙ-ХЛОР-КОТРАНСПОРТ В РЕГУЛЯЦИИ МИОГЕННОГО ТОНУСА СОСУДОВ

The article discusses the data on the functioning of Na + ,K + ,2Cl – cotransport – the carrier providing electroneutral symport of sodium, potassium and chloride, as well as molecular mechanisms of the regulation and physiological significance of this carrier. We analyzed the novel data on involvement of ubiquitous isoform of Na + ,K + ,2Cl – cotransporter (NKCC1) in regulation of vascular smooth muscle contraction, and role of this carrier in the regulation of cell volume and intracellular chloride concentration.

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来源期刊

Byulleten Sibirskoy Meditsiny MEDICINE, GENERAL & INTERNAL-

CiteScore

0.70

自引率

50.00%

发文量

102

审稿时长

8 weeks